The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children and the second leading cause of infant death worldwide. While global circulation has been extensively studied for respiratory viruses such as seasonal influenza, and more recently also in great detail for SARS-CoV-2, a lack of global multi-annual sampling of complete RSV genomes limits our understanding of RSV molecular epidemiology.

Citation:
Langedijk AC, Vrancken B, Lebbink RJ, ......... Richmond P, Martinon-Torres F, ....... Wadia U et al for the INFORM-RSV Study Group. The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus. Nat Commun. 2024;15(1):3083

Keywords:
Genomics; phylogeny; respiratory syncytial virus; infections; epidemiology; genetics

Abstract:
Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infection in young children and the second leading cause of infant death worldwide. While global circulation has been extensively studied for respiratory viruses such as seasonal influenza, and more recently also in great detail for SARS-CoV-2, a lack of global multi-annual sampling of complete RSV genomes limits our understanding of RSV molecular epidemiology.