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Clinical Predictors of Longitudinal Respiratory Exacerbation Outcomes in Young Hospitalised Children

Respiratory infection and wheezing illness are leading causes of hospitalisation in childhood, placing a significant burden on families and healthcare systems. However, reliably distinguishing children at risk of developing persistent disease from those likely to outgrow their symptoms remains a clinical challenge. Earlier identification would allow clinicians to focus care and resources on those most likely to benefit from long-term management, while reducing anxiety and uncertainty about the future for families.

Citation:
Coleman LA, Khoo SK, Franks K, Prastanti F, Leffler J, Le Souëf PN, Karpievitch YV, Hancock DG, Laing IA. Clinical Predictors of Longitudinal Respiratory Exacerbation Outcomes in Young Hospitalised Children. Clin Exp Allergy. 2025.

Keywords:
Acute asthma; asthma exacerbation; childhood; risk factors; wheezing

Abstract:
Respiratory infection and wheezing illness are leading causes of hospitalisation in childhood, placing a significant burden on families and healthcare systems. However, reliably distinguishing children at risk of developing persistent disease from those likely to outgrow their symptoms remains a clinical challenge. Earlier identification would allow clinicians to focus care and resources on those most likely to benefit from long-term management, while reducing anxiety and uncertainty about the future for families.