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Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth Cohort

Food allergy affects families' quality of life, can be lifelong and life-threatening, urging the identification of early modifiable risk factors. Formula feeding in the first days of life may increase the risk of cow's milk allergy, a risk often attributed to cow's milk allergens exposure. Early formula feeding also reduces the colostrum intake, the first 3 days' milk, which is rich in bioactive compounds critical for immune and gut health. This study investigates whether partial colostrum feeding increases the risk of food allergy beyond cow's milk.

Citation:
Bhasin M, Cooper M, Macchiaverni P, Joys RS, O'Sullivan TA, Keelan JA, Venter C, Palmer DJ, Lowe AJ, Prescott SL, Silva D, Verhasselt V. Colostrum as a Protective Factor Against Peanut Allergy: Evidence From a Birth Cohort. Allergy: European Journal of Allergy and Clinical Immunology. 2025.

Keywords:
Food allergy; nutrition; paediatrics; prevention

Abstract:
Food allergy affects families' quality of life, can be lifelong and life-threatening, urging the identification of early modifiable risk factors. Formula feeding in the first days of life may increase the risk of cow's milk allergy, a risk often attributed to cow's milk allergens exposure. Early formula feeding also reduces the colostrum intake, the first 3 days' milk, which is rich in bioactive compounds critical for immune and gut health. This study investigates whether partial colostrum feeding increases the risk of food allergy beyond cow's milk.