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Numerical simulation of aerosolised medicine delivery through tracheostomy airways

The administration of inhaled antibiotics to patients with upper or lower respiratory infections is sometimes conducted via a tracheostomy airway. However, precise dosing via this route remains uncertain, especially in spontaneously breathing paediatric patients. 

Citation:
Gumulya M, Anderson NVE, Mead-Hunter R, von Ungern-Sternberg BS, Mullins BJ. Numerical simulation of aerosolised medicine delivery through tracheostomy airways. Journal of Aerosol Science. 2026;191.

Keywords:
Computational fluid dynamics (CFD); Eulerian–Lagrangian approach; Pharmaceutical aerosols; Polydisperse aerosols; Aerosol deposition; Respiratory drug delivery

Abstract:
The administration of inhaled antibiotics to patients with upper or lower respiratory infections is sometimes conducted via a tracheostomy airway. However, precise dosing via this route remains uncertain, especially in spontaneously breathing paediatric patients.