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Directing immune development to curb sky-rocketing diseaseOnce upon a time it was infectious diseases like polio, measles or tuberculosis that most worried parents. With these threats now largely under control, parents face a new challenge – sky-rocketing rates of non-infectious diseases such as asthma, allergies and autism.
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Chemical analysis of new and “aged” e-liquids: Development of a rapid toxicological screening approachInvestigators: Alexander Larcombe Project description This study investigated the chemical composition of electronic cigarette liquids (e-liquids)
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Investigating the effects of macrolides on excessive synthesis and secretion of airway mucins using novel ex vivo and in vivo approachesInvestigators: Alexander Larcombe, Emily Chivers External collaborators: Professor Peter Henry (University of Western Australia) Plain language
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Lung function in a model of a paediatric metabolic diseaseInvestigators: Alexander Larcombe, Emily Chivers Project description Lysosomes are structures within the cells of the body with the job of breaking
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Biodiesel exhaust: The need for a systematic approach to health effects researchBiodiesel is a generic term for fuel that can be made from virtually any plant or animal oil via transesterification of triglycerides with an alcohol...
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Respiratory toxicology of e-cigarettes: effect of vapours on lung function and inflammationElectronic cigarettes (ECs) have been rapidly gaining ground on conventional cigarettes due to their efficiency in ceasing or reducing tobacco consumption,...
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In utero exposure to low dose arsenic via drinking water impairs early life lung mechanics in miceAll alterations to lung mechanics following in utero arsenic exposure were recovered by adulthood.
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The mechanism of deep inspiration-induced bronchoprotection: Evidence from a mouse modelIn healthy individuals, deep inspirations (DIs) taken prior to a bronchial challenge reduce the bronchoconstrictor response, which is termed...
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Emerging issues in the Pacific BasinThis review provides a snapshot of some key environmental health issues that will provide ongoing challenges for the Pacific Basin region in the coming decades
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No role for neutrophil elastase in influenza-induced cellular recruitment, cytokine production or airway hyperresponsiveness in micePrevious studies have suggested that in vitro modulation of neutrophil chemokines and inflammatory cytokines by neutrophil elastase (NE) does not translate to t