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Few children and adolescents receiving BPG as secondary prophylaxis will achieve concentrations >0.02 mg/L for the majority of the time between injections
Acute rheumatic fever is infrequently diagnosed in sub-Saharan African countries despite the high prevalence of rheumatic heart disease. We aimed to determine the incidence of acute rheumatic fever in northern and western Uganda.
This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin O titres (ASOT) from dried blood spot (DBS) samples
Surgical intervention is an important treatment modality for advanced rheumatic heart disease (RHD). This study aimed to describe patient characteristics and outcomes from cardiac surgery for RHD in patients referred to the only tertiary paediatric hospital in Western Australia.
Acute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia.
We aimed to review RHD burden in Western Pacific Region outside Oceania to identify countries with high RHD burden
A 7-year old boy developed myositis secondary to intramuscular injection of benzathine penicillin-G in the context of secondary prophylaxis for RF
A sample target product profile for reformulated benzathine penicillin G is presented
The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century.
Reliable supplies of BPG are essential for delivering the recommended schedule of secondary prophylaxis for people living with RHD.