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The global burden of non-communicable diseases (NCDs) continues to grow. Although developing settings face fastest growth in incidence, no country is exempt.

The association between group A streptococcal infection and rheumatic fever (RF) was established in the early 20th century.

This editorial refers to ‘Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart...

The review built a case for extending simple and cost–effective measures to all countries. Had these recommendations been put into action, significant...

We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996.

Building on the foundation of the first RHD forum, over 150 interested participants met to discuss critical issues on the RHD landscape.

Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator.

The reduction in ARF recurrence indicates that the RHD control program has improved secondary prophylaxis; a decline in RHD incidence is expected to follow.

Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.

The desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease.