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Prevention - what is the most promising approach?This paper is an editorial comment by Professor Patrick Holt on the potential for developing early intervention strategies in children with allergies and asthma
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Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell PopulationsThe respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...
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Maternal Vitamin D Levels and the Autism Phenotype Among OffspringWe tested whether maternal vitamin D insufficiency during pregnancy is related to the autism phenotype.
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Vitamin D and atopy and asthma phenotypes in childrenThe purpose of this Review was to give an overview of the recent research into whether a lack of vitamin D contributes to the development of atopy and asthma...
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Sensitizing and Th2 Adjuvant Activity of Cysteine Protease AllergensHere, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa.
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Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodesInhaled allergens are known for their immediate and ongoing effects in the respiratory tract (RT).
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Th2-polarisation of cellular immune memory to neonatal pertussis vaccinationCurrent infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular...
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Early aberrant antibody responses of aeroallergen sensitised people to subclinical bacterial infectionEarly aberrant antibody responses, aeroallergen sensitised people, subclinical bacterial infection
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Gene polymorphisms, breast-feeding, and development of food sensitization in early childhoodThe effect of breast-feeding on the development of allergic disease is uncertain
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Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...