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Research

In Vivo Evidence of Respiratory Syncytial Virus Persistence in a Subset of Pulmonary Dendritic Cells Following a Primary Infection

Respiratory syncytial virus (RSV) causes annual epidemics of infections affecting the whole population. In vitro, it has been shown to infect and persist in human dendritic cells (DCs) for prolonged periods. Initially persistence is associated with low levels of replication before the virus becomes dormant. Reactivation of viral replication can be triggered many months later.

Research

Nonchromosomal birth defects and risk of childhood acute leukemia: An assessment in 15 000 leukemia cases and 46 000 controls from the Childhood Cancer and Leukemia International Consortium

Although recent studies have demonstrated associations between nonchromosomal birth defects and several pediatric cancers, less is known about their role on childhood leukemia susceptibility. Using data from the Childhood Cancer and Leukemia International Consortium, we evaluated associations between nonchromosomal birth defects and childhood leukemia.

Research

RISING STARS: The heat is on: how does heat exposure cause pregnancy complications?

The incidence and severity of heatwaves are increasing globally with concomitant health complications. Pregnancy is a critical time in the life course at risk of adverse health outcomes due to heat exposure. Dynamic physiological adaptations, which include altered thermoregulatory pathways, occur in pregnancy.

Modelling for the health of our next generation

Nearly 170 years ago a British doctor applied geospatial mapping to identify the source of a cholera outbreak in central London.

FASD Hub a one-stop-shop for research and information for professionals and parents

A website providing the latest research and resources on Fetal Alcohol Spectrum Disorder (FASD) is helping parents, educators, health professionals and policy makers navigate the complexities of the neurodevelopmental impairment condition.

How researchers have made surgery for babies

The Kids Research Institute Australia’s Perioperative Medicine team is helping to change global and local practice by finding safer and gentler ways to both undertake surgery, and care for kids and families afterwards.

Giving kids with CF a chance at a longer, healthier life

COMBAT CF is one of two long-standing international trials which have resulted in new early intervention options helping to reduce progressive lung damage in kids living with CF.

News & Events

Shopping For Data to Drive Discoveries

What if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?

News & Events

ORIGINS Ch7 News Story

ORIGINS featured on Channel 7 News recently with two family stories of how ORIGINS changed their lives.

News & Events

Tips for protecting your baby in the summer heat

Paediatrician Dr Lana Bell shares her top tips for keeping your baby or toddler cool, well-hydrated and protected as the temperature soars.