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Research
Sensitizing and Th2 Adjuvant Activity of Cysteine Protease AllergensHere, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa.
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Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell PopulationsThe respiratory tract is an attractive target organ for novel diagnostic and therapeutic applications with nano-sized carriers, but their immune effects and...
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Early aberrant antibody responses of aeroallergen sensitised people to subclinical bacterial infectionEarly aberrant antibody responses, aeroallergen sensitised people, subclinical bacterial infection
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Th2-polarisation of cellular immune memory to neonatal pertussis vaccinationCurrent infant vaccination against pertussis in North America and Australia requires three doses of vaccines including diphtheria, tetanus and acellular...
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Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodesInhaled allergens are known for their immediate and ongoing effects in the respiratory tract (RT).
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Immunobiology & Immunotherapeutic ProgramListed are The Kids Research Institute Australia research teams involved in our Immunity and Inflammation Program. This program sits under the Early Environment research theme.
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Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profilesthe association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories
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Assessment of the potency and potential immunomodulatory effects of the Measles Mumps Rubella-Varicella vaccine in infantsThis study compared the potency and immunomodulatory effects of measles mumps rubella (MMR) vaccine given to infants alone or in combination with varicella...
Research
Asthma: Acute asthma flare-up in school-age childrenThe aim of this study is to identify differences in immune cells that are involved in the disease.
