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Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female miceEarly life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice
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Biodiesel exhaust-induced cytotoxicity and proinflammatory mediator production in human airway epithelial cellsOur results show that canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared...
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Regional Differences in Susceptibiity of Bronchial Epithelium to Mesenchymal Transition and Inhibition by the Macrolide Antibiotic AzithromycinDysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured...
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DNA Methylation Profiles of Airway Epithelial Cells and PBMCs from Healthy, Atopic and Asthmatic ChildrenAllergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis.
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Deep inspiration and airway physiology: human, canine, porcine, or bovine?Deep inspiration and airway physiology: human, canine, porcine, or bovine?
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A tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for the treatment and prevention of Group A Streptococcus infectionsAnthony Tim Kicic Barnett BSc (Hons) PhD PhD Rothwell Family Fellow; Head, Airway Epithelial Research Head, Strep A Pathogenesis and Diagnostics
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Pre-Post Intervention to Strengthen and Sustain the Paediatric ESCALATION System (The SPECS): Study ProtocolPromptly recognising changes in an acutely unwell child’s condition is fundamental to prevent tragic outcomes. Western Australian (WA) healthcare facilities used inconsistent and varied paediatric early warning systems. To improve care consistency, a standardised ESCALATION system, inclusive of family involvement and sepsis recognition, was developed.
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Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial CellsApically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces.
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Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cellsThis study assessed an alternative approach, using a small scale halide assay that can be adapted for a personalized high throughput setting to analyze CFTR function of pAEC.