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In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype

In this review we explore the current literature about the predictive characteristics of the tumor microenvironment and discuss therapeutic approaches

Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers

Children with Primary Central Nervous System Lymphoma and no immunodeficiency have a good outcome

Our findings provide some evidence of an association between maternal smoking during pregnancy and Neuroblastoma

Invasive fungal infections are more common in children with high-risk acute lymphoblastic leukaemia and in relapsed disease

We did not find any associations between parental occupational extremely low-frequency magnetic fields exposure and childhood leukaemia

The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours

This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response