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Expiratory flow limitation and breathing strategies in overweight adolescents during submaximal exerciseYoung people who are overweight/obese are more likely to display expFL during submaximal exercise compared with children of healthy weight.
Research
Reference values for spirometry: The way forward for our patientsFew clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes.
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Performance Accuracy of Wrist-Worn Oximetry and Its Automated Output Parameters for Screening Obstructive Sleep Apnea in ChildrenObstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool.
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Elevated leukotriene B4 and 8-isoprostane in exhaled breath condensate from preterm-born infantsInflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity.
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Development of an International Database for a Rare Genetic Disorder: The MECP2 Duplication Database (MDBase)The natural history of MECP2 duplication syndrome (MDS), a rare X-linked neurodevelopmental disorder with an estimated birth prevalence of 1/150,000 live births, is poorly understood due to a lack of clinical data collected for research. Such information is critical to the understanding of disease progression, therapeutic endpoints and outcome measures for clinical trials, as well as the development of therapies and orphan products.
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The Global Lung Function Initiative (GLI) Network ERS Clinical Research Collaboration: how international collaboration can shape clinical practiceThe Global Lung Function Initiative is working to improve the interpretation of lung function: an update on current work and the opportunities for further engagement
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Maternal exposure to indoor air pollution and birth outcomesAlthough formaldehyde concentrations were very low, this finding is consistent with other studies of formaldehyde and poor birth outcomes
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Could home-based FeNO measurements breathe new life into asthma management?Developing a FeNO test that is affordable enough to allow daily measurements, patients will be able to access quantifiable data to assist them to monitor their asthma
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Inhalational versus Intravenous Induction of Anesthesia in Children with a High Risk of Perioperative Respiratory Adverse Events: A Randomized Controlled TrialAnesthesiologists should consider using an intravenous propofol induction technique in children who are at high risk of experiencing perioperative respiratory adverse event
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Technical standards for respiratory oscillometryThe aim of the task force was to provide technical recommendations regarding oscillometry measurement