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Research

Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic drugs, little clinical evidence exists to support this recommendation.

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The effects of JASPER intervention for children with autism spectrum disorder: A systematic review

Naturalistic developmental behavioural interventions are promising approaches for young children with, or suspected of having, autism spectrum disorder. Joint attention, symbolic play, engagement and regulation intervention (JASPER) is a well-researched naturalistic developmental behavioural intervention but, to date, no reviews have specifically evaluated its effects.

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Occurrence of psychosis and bipolar disorder in adults with autism: A systematic review and meta-analysis

Evidence suggests that individuals with autism spectrum disorder have increased rates of co-occurring psychosis and/or bipolar disorder. Considering the peak age of onset for psychosis and bipolar disorder occurs in adulthood, we investigated the co-occurrence of these disorders in adults with autism.

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Evidence of a reduction over time in the behavioral severity of autistic disorder diagnoses

We examined whether there were changes over time in the qualitative and quantitative phenotype of individuals who received the diagnosis of Autistic Disorder.

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Hypertensive diseases of pregnancy predict parent-reported difficult temperament in infancy

These data suggest that the link between maternal hypertensive diseases of pregnancy and child behavioral development begins in the first year of life.

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Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms

Pregnancy is a time of vulnerability for vitamin D insufficiency, and there is an emerging literature associating low levels of 25(OH)-vitamin D with...

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A Genome-wide Association Meta-analysis of Preschool Internalizing Problems

In this study, the influence of genome-wide measured single nucleotide polymorphisms (SNPs) was investigated in 3 cohorts (total N = 4,596 children) in which...

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Moving beyond behaviour-only assessment: Incorporating biomarkers to improve the early detection and diagnosis of autism spectrum disorders

This paper presents a response to the Camarata (2014) lead article regarding the accuracy and effectiveness of early identification and early intervention...

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High use of complementary and alternative medication among children with autism is not associated with the severity of core symptoms

This study provided evidence for high rate of alternative medicine use in an Australian paediatric ASD population, similar to other countries.

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Genome-wide association study of autistic-like traits in a general population study of young adults

Research has proposed that autistic-like traits in the general population lie on a continuum, with clinical ASD representing the extreme end of this...