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Expiratory flow limitation and breathing strategies in overweight adolescents during submaximal exerciseYoung people who are overweight/obese are more likely to display expFL during submaximal exercise compared with children of healthy weight.
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Emerging Early Life Environmental Exposures and Lung DevelopmentIn this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking...
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The safety and feasibility of the inhaled mannitol challenge test in young childrenMannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6...
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Infection, inflammation,and lung function decline in infants with cystic fibrosisBetter understanding of evolution of lung function in infants with cystic fibrosis...
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Reference values for spirometry: The way forward for our patientsFew clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes.
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Characterization of maximal respiratory pressures in healthy childrenMeasurements of maximal voluntary inspiratory (Pi max) and expiratory (Pe max) pressures are used in the management of respiratory muscle disease...
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Lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected ageTo assess whether lung volume and ventilation inhomogeneity in preterm infants at 15-18 months corrected age
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The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS Clinical Research Collaboration: understanding the impact of preterm birth on lung health throughout lifeAn estimated 15 million babies (∼11%) are born preterm each year (before 37 weeks of gestation), the rates of which are increasing worldwide. Enhanced perinatal care, including antenatal corticosteroids, postnatal surfactant and improved respiratory management, have markedly improved survival outcomes since the 1990s, particularly for babies born very preterm (<32 weeks gestation). However, long-term pulmonary sequelae are frequent in preterm survivors and ongoing clinical management is often required.
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Pulmonary Gas Exchange Improves over the First Year in Preterm Infants with and without Bronchopulmonary DysplasiaRight shift of the peripheral oxyhaemoglobin saturation (SpO2) versus inspired oxygen pressure (PIO2) curve is a sensitive marker of pulmonary gas exchange. The aim of this study was to assess the impact of prematurity and bronchopulmonary dysplasia (BPD) on gas exchange and right-to-left shunt in the neonatal period, and its evolution over the first year of life.
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Does machine learning have a role in the prediction of asthma in children?Asthma is the most common chronic lung disease in childhood. There has been a significant worldwide effort to develop tools/methods to identify children's risk for asthma as early as possible for preventative and early management strategies. Unfortunately, most childhood asthma prediction tools using conventional statistical models have modest accuracy, sensitivity, and positive predictive value.