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Local researchers lead biggest ‘artificial pancreas’ outpatient study

The Children’s Diabetes Centre at The Kids Research Institute Australia is leading the longest and largest at-home trial of a hybrid closed-loop insulin pump system.

Informing Resource Allocation for Investment in Early Childhood: A Review of the International Peer-Reviewed Evidence

Early childhood investment decisions represent critical policy frameworks that ideally reflect a strong evidence base. This review seeks to assess early childhood intervention priorities based on return on investment without limitation by health, education or social science sector.

Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection

Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1beta signaling plays an important role in GAS disease progression.

Prophage exotoxins enhance colonization fitness in epidemic scarlet fever-causing Streptococcus pyogenes

The re-emergence of scarlet fever poses a new global public health threat. The capacity of North-East Asian serotype M12 (emm12) Streptococcus pyogenes (group A Streptococcus, GAS) to cause scarlet fever has been linked epidemiologically to the presence of novel prophages

Recombinational exchange of M-fibril and T-pilus genes generates extensive cell surface diversity in the global group A Streptococcus population

Among genes present in all group A streptococci (GAS), those encoding M-fibril and T-pilus proteins display the highest levels of sequence diversity, giving rise to the two primary serological typing schemes historically used to define strain. A new genotyping scheme for the pilin adhesin and backbone genes is developed and, when combined with emm typing, provides an account of the global GAS strain population.

Play Active Program – physical activity policy and training for Early Childhood Education and Care

Play Active is a national, low-cost, evidence-based program to boost energetic play in early childhood education and care. It offers free professional development for educators.

Levels of innate immune factors in preterm and term mothers' breast milk during the 1st month postpartum

Preterm breast milk contains significantly higher concentrations of some immune proteins than term breast milk

Coping with COVID-19

In this blog, Clinical Psychology Lead Dr Mei’en Lim offers families advice on how to navigate COVID-19 with an autistic child.

Podcast

Embracing the Mind is hosted by Embrace senior researchers Dr Alix Woolard and Dr Karen Lombardi.

The relationship between physical activity, self-regulation and cognitive school readiness in preschool children

Limited research exists on the pathways through which physical activity influences cognitive development in the early years. This study examined the direct and indirect relationships between physical activity, self-regulation, and cognitive school readiness in preschool children.