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Research

Epigenomic variability is associated with age-specific naïve CD4 T cell response to activation in infants and adolescents

Childhood is a critical period of immune development. During this time, naïve CD4 T cells undergo programmed cell differentiation, mediated by epigenetic changes, in response to external stimuli leading to a baseline homeostatic state that may determine lifelong disease risk. However, the ontogeny of epigenetic signatures associated with CD4 T cell activation during key developmental periods are yet to be described.

News & Events

Major milestone for Early Moves; a key sub-project of ORIGINS investigating early signs of learning difficulties in babies

Ground-breaking WA-led study, Early Moves has hit a major milestone, with 3,000 participants successfully recruited over a four-year period. 

News & Events

WA Cohorts Network welcomes FHRI Funding Announcement

The State Government has launched the new WA Cohort Studies Research Project Support Program, recognising the value and importance of the three major cohort studies in WA.

News & Events

New funding supports program to create "happier" parents

New funding from Channel 7 Telethon Trust is allowing ECU researchers to work with ORIGINS families to investigate how parents and their babies can best be supported in the first year.

News & Events

COVID-19 Update: Perth Lockdown 3 July 2021

ORIGINS is moving to virtual appointments and couriers to collect home samples during the June 2021 Perth lockdown.

News & Events

Baby's Social and Developmental Milestones

Paediatrician Dr Lana Bell's tips on identifying baby developmental milestones

News & Events

Parents be alert but not alarmed

There is no doubt that developmental milestones play a very important role for parents.

News & Events

Aveley parents sign up ORIGINS

Cara and Peter signed up to The ORIGINS Project in 2017 when Cara was only six months pregnant with their first child, Oscar.

News & Events

Key milestones delayed as parents spend more time on devices

Leading paediatrician and Co-Director of ORIGINS Professor Desiree Silva says key developmental milestones like smiling are being delayed because parents are spending too much time on devices.

For researchers

ORIGINS is a community resource that invites collaborative sub-projects and initiatives.