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Research
Impaired interferon response in plasmacytoid dendritic cells from children with persistent wheezeImpaired interferon response and allergic sensitization may contribute to virus-induced wheeze and asthma development in young children. Plasmacytoid dendritic cells play a key role in antiviral immunity as critical producers of type I interferons.
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NHMRC funding awarded to support child health researchThe Kids Research Institute Australia researchers have been awarded more than $10 million in research funding from the National Health and Medical Research Council (NHMRC).
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Switch on the immune system earlyFindings by Professor Pat Holt revealed researchers had been heading down the wrong path in their battle strategy against respiratory allergy and asthma.
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Overseas trip will help unlock the asthma puzzleOne in ten Australians have asthma and Dr Kimberley Wang from The Kids Research Institute Australia is on a mission to find out what causes it.
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Volunteers needed for world-first trial to prevent asthmaAustralian scientists have today launched a world first research trial into a treatment that could prevent asthma in high risk children.
Research
Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo modelsThis paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD.
Research
Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infectionAsthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C.
Research
Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthmaThese data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...
Research
Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cellsThe airway epithelium in asthma displays altered repair and incomplete barrier formation.
Research
IgE and IgG binding patterns and T-cell recognition of fel d 1 and Non-Fel d 1 cat allergensTo compare IgE and IgG antibody binding and T-cell recognition of the major cat allergen Fel d 1 with other cat proteins with known IgE binding properties.