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Research

Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection

Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C.

Research

Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...

Research

Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cells

The airway epithelium in asthma displays altered repair and incomplete barrier formation.

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Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models

This paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD.

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Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets

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Prevention of Allergy/Asthma - New Strategies

This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches

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The genetic and epigenetic landscapes of the epithelium in asthma

Genetic factors in airway epithelial cells that are functionally associated with asthma pathogenesis

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Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

Review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context

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Longer duration of exclusive breastfeeding associated with reduced risk of childhood asthma up to age six

Breastfeeding is recommended for all infants irrespective of atopic heredity, although epidemiological studies provide conflicting results in this debate.

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Global strategy for the diagnosis and management of asthma in children 5 years and younger

Asthma is the most common chronic disease of childhood and the leading cause of childhood morbidity from chronic disease as measured by school absences...