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Gut microbiome and innate immune response patterns in IgE-associated eczema

Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling.

Maternal fish oil supplementation in pregnancy: a 12 year follow-up of a randomised controlled trial.

We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine...

The maturation of immune functions in pregnancy and early childhood

This book chapter explains the maturation of immune functions during pregnancy & in early childhood, and addresses the importance of early environmental...

Prevention and Natural History of Food Allergy

The rise in food allergy is more rapid than genetic deviation would allow and the current consensus is that environmental factors integrally linked to the...

Developing primary intervention strategies to prevent allergic disease

Allergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating.

Effects of maternal n-3 fatty acid supplementation on placental cytokines, pro-resolving lipid mediators and their precursors

The aim of this study was to determine whether supplementation with fish oil-derived n-3 PUFA during pregnancy modifies modifies placental PUFA composition...

Blood DNA methylation biomarkers predict clinical reactivity in food-sensitized infants

The diagnosis of food allergy (FA) can be challenging because approximately half of food-sensitized patients are asymptomatic.

Analytical bias in the measurement of plasma 25-hydroxyvitamin D concentrations in infants

To our knowledge, this is the first study to show that the reported 25(OH)D concentration may be influenced by both age and assay type

High-Rise Apartments and Urban Mental Health—Historical and Contemporary Views

High-rise apartment buildings have long been associated with the poor mental health of their residents