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CDKL5 Deficiency Disorder (CDD) is a rare neurodevelopmental disorder characterised by early onset seizures combined with complex healthcare needs and developmental impairment that influence functional domains including communication. Communication is a high priority domain for families but currently used measures demonstrate floor effects.
High-grade glioma (HGG) cells reactivate neurodevelopmental programs regulated by ion channels to drive tumor progression. The activity of voltage-gated sodium channels (VGSCs) is fundamental to development, a target of blood-brain barrier (BBB)-permeable FDA-approved drugs, and aids tumor advancement in several cancers. However, the contribution of VGSC activity to HGG pathology remains unknown.
Malaria is a focal disease and more localized in low endemic areas. The disease is increasingly becoming a concern in urban areas in most sub-Saharan African countries. The growing threats of Anopheles stephensi and insecticide resistance magnify this concern and hamper elimination efforts. It is, therefore, imperative to identify areas, within urban settings, of high-risk of malaria to help better target interventions.
Discover the impact of our achievements in the "real world".
The Institute farewelled one of its most treasured employees this year, as The Kids Cancer Centre research officer Jette Ford closed the door on a quietly stellar 37-year career which has helped to change the face of cancer research in WA and around the world.
Researchers leading WA’s landmark ORIGINS Project have spearheaded a global network that will see them join forces with similar interventional cohort studies across the world to maximise data collection and learnings for
A global network of researchers led by Kerry M Stokes Chair of Child Health, Professor Pete Gething, is working to help support informed decision-making for malaria control at international, regional and national scales.
The world’s leading preterm scientists and doctors have joined forces to help give babies born very prematurely, the best possible life.
Running any research project is a feat of logistical gymnastics – and often, you don’t know what can go wrong until it happens.
In early 2021, The Kids Research Institute Australia researcher Dr Amy Finlay-Jones led a global team in trying to answer that question to help better prioritise mental health spending.