Search

News & Events

ORIGINS BENEFIT study is looking at whether mums eating more allergenic foods during pregnancy and early breastfeeding would make a difference to their children developing allergies.

Research

Respiratory Syncytial Virus (RSV) causes a significant burden of illness for children under 2 years of age. Nirsevimab, a long-acting monoclonal antibody, was registered for RSV prevention in Australia in 2023. In April 2024, Western Australia (WA) launched the country's first state-wide nirsevimab program for all infants and high-risk children entering their second RSV season. 

Research

The abstract screening process of systematic reviews can take thousands of hours by two researchers. We aim to determine the reliability and validity of Research Screener, a semi-automated abstract screening tool within a systematic review on non-specific and broader effects of respiratory vaccines on acute lower respiratory infection hospitalisations and antimicrobial prescribing patterns in young children.

Research

Respiratory syncytial virus (RSV) remains a leading cause of mortality and morbidity worldwide. RSV seasonality was disrupted by COVID-19-associated nonpharmaceutical interventions (NPIs). We review RSV seasonality, molecular epidemiology, clinical manifestations, and community awareness to inform future prevention strategies. 

Research

First Nations children hospitalised with acute lower respiratory infections (ALRIs) are at increased risk of future bronchiectasis (up to 15-19%) within 24-months post-hospitalisation. An identified predictive factor is persistent wet cough a month after hospitalisation and this is likely related to protracted bacterial bronchitis which can progress to bronchiectasis, if untreated.

News & Events

One of the more common food allergies ORIGINS is seeing in babies is cow’s milk protein allergy (CMPA).

Research

Climatic conditions play a key role in the transmission and pathophysiology of respiratory tract infections, either directly or indirectly. However, their impact on the COVID-19 pandemic propagation is yet to be studied.

Research

Acute wheezing is one of the most common hospital presentations for young children. Respiratory syncytial virus (RSV) and rhinovirus (RV) species A, B and the more recently described species C are implicated in the majority of these presentations. However, the relative importance and age-specificities of these viruses have not been defined.

Research

Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice a maternal low-fiber diet led to enhanced LRI severity in infants because of delayed plasmacytoid dendritic cell recruitment and perturbation of regulatory T cell expansion in the lungs.

News & Events

How to identify and tackle a weight problem in children is a delicate and sensitive issue for many parents. However, the earlier any child weight issues are identified the better.

Research

Pregnancy and early infancy are increased risk periods for severe adverse effects of respiratory infections. Aboriginal and/or Torres Strait Islander (respectfully referred to as First Nations) women and children in Australia bear a disproportionately higher burden of respiratory diseases compared to non-Indigenous women and infants. Influenza vaccines and whooping cough (pertussis) vaccines are recommended and free in every Australian pregnancy to combat these infections.

News & Events

Professor Andrew Whitehouse and the Autism team at The Kids are working with Joondalup Health Campus as part of ORIGINS to gain greater insight into how the brain develops in children who have difficulties with language.

News & Events

Almost one in five children across four remote Kimberley communities has some form of chronic lung disease, according to a new study co-designed and conducted in partnership with Aboriginal communities.

News & Events

ORIGINS is investigating the influence of nature, from pregnancy through the early years of childhood and its impact on later health, as part of the nature relatedness study.

News & Events

Charlie, 6, has ended up in hospital twice with invasive Strep A infection over his short lifetime – the first time when just three years old.

News & Events

While learning language is a lifelong journey, the first few years of life are especially important. So how do you know if your child’s language is on track?

Thanks for being part of the ORIGINS Facebook group! See our favourite iron rich recipes below.

News & Events

The episode investigates the alarming rise in early-onset adult cancers and the research efforts to understand why and what Australia can do the reduce its diagnoses.

ORIGINS is collecting data from multiple sources from the mother, infant and partner at multiple timepoints from gestation through to five years of age.

A list of documents, forms and resources for current or potential collaborators to download