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Maternal Late-Pregnancy Serum Unmetabolized Folic Acid Concentrations Are Not Associated with Infant Allergic Disease: A Prospective Cohort Study

The increase in childhood allergic disease in recent decades has coincided with increased folic acid intakes during pregnancy. Circulating unmetabolized folic acid (UMFA) has been proposed as a biomarker of excessive folic acid intake. We aimed to determine if late-pregnancy serum UMFA and total folate concentrations were associated with allergic disease risk in the offspring at 1 y of age in a population at high risk of allergy.

Developmental Origins of Health and Disease (DOHaD): The importance of life-course and transgenerational approaches

With well-established evidence that early life conditions have a profound influence on lifespan and health-span, new interventional birth cohorts are examining ways to optimise health potential of individuals and communities. These are aimed at going beyond preventing disease, to the conditions that facilitate flourishing from an early age.

Environmental (Perinatal) risk factors of ADHD in a sibling control design study

Citation: Ibilola O, Silva D. Environmental (Perinatal) risk factors of ADHD in a sibling control design study. Open Access Journal of Behavioural

ORIGINS

ORIGINS is the largest study of its kind in Australia, following 10,000 children, from their time in the womb, over a decade to improve child and adult health.

Benefits for ORIGINS families

ORIGINS is an interventional cohort study, meaning participants receive timely feedback and an action plan to address any potential abnormalities.

Papers & Publications

Publications, papers and findings coming out of ORIGINS and its sub-projects

ORIGINS: A Unique World Class Interventional Research Enabling Platform

An interventional birth cohort researching ways to optimise health and identify conditions that enable every child to flourish from an early age.

Generation Australia

A unique national platform delivering faster research at scale to improve the health, wellbeing and equity of children and their parents across Australia

ORIGINS begins collecting baby teeth to unlock new insights into child health research.

All participating families to receive $10 e-voucher for this generous donation.*

International Women's Day 2025

Hear from Avril Bezant, ORIGINS Data Coordinator, and Alexis Harun, ORIGINS Paediatric Coordinator, and be reminded that it’s never too late to pursue your passion along with their hopes for women entering a STEM career.