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Pre- and probiotics for allergy prevention: time to revisit recommendations?We discuss how the choice of probiotic strains, timing and duration of administration can critically influence the outcome due to different effects on immune modulation and gut microbiota composition
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Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable DiseasesA better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): PrebioticsDevelop evidence-based recommendations about the use of prebiotics in the prevention of allergy
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Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczemaElevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg
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Assessment of cardiometabolic risk in children in population studies: underpinning developmental origins of health and disease mother–offspring cohort studiesPregnancy and birth cohorts have been utilised extensively to investigate the developmental origins of health and disease, particularly in relation to...
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Autism spectrum disorder in children born preterm: Role of exposure to perinatal inflammationThis review aims to summarise and evaluate the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it...
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Effects of pregnancy and lactation prebiotics supplementation on infant allergic disease: A randomized controlled trialIngestion of prebiotics during pregnancy and lactation may have immunomodulatory benefits for the developing fetal and infant immune system and provide a potential dietary strategy to reduce the risk of allergic diseases. We sought to determine whether maternal supplementation with dietary prebiotics reduces the risk of allergic outcomes in infants with hereditary risk.
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“Food faddists and pseudoscientists!”: Reflections on the history of resistance to ultra-processed foodsThe term 'ultra-processed food' emerged in the 1980s, mostly used in reference to highly-processed convenience foods and snacks, often energy-dense, poor in nutrients, and inclusive of various synthetic additives such as emulsifiers, colors, artificial sweeteners, and/or flavor enhancers.
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Feasibility and safety of introducing cashew nut spread in infant diets-A randomized trialTo reduce peanut allergy prevalence, infant feeding guidelines now recommend introducing peanuts in an age-appropriate form (such as peanut butter) as part of complementary feeding. However, due to a lack of randomized trial evidence, most infant feeding and food allergy prevention guidelines do not include tree nuts. The aims of this trial were to determine safety and feasibility of dosage consumption recommendations for infant cashew nut spread introduction.
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‘It’s been a lifelong thing for me’: parents’ experiences of facilitating a healthy lifestyle for their children with severe obesityFor parents and guardians, assisting children/adolescents with severe obesity to lose weight is often a key objective but a complex and difficult challenge. Our aim in this study was to explore parents' (and guardians') perspectives on the challenges they have faced in assisting their children/adolescents with severe obesity to lead a healthy lifestyle.