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Immunogenicity, reactogenicity, and IgE-mediated immune responses of a mixed whole-cell and acellular pertussis vaccine schedule in Australian infants: A randomised, double-blind, noninferiority trial

In many countries, infant vaccination with acellular pertussis (aP) vaccines has replaced use of more reactogenic whole-cell pertussis (wP) vaccines. Based on immunological and epidemiological evidence, we hypothesised that substituting the first aP dose in the routine vaccination schedule with wP vaccine might protect against IgE-mediated food allergy. We aimed to compare reactogenicity, immunogenicity, and IgE-mediated responses of a mixed wP/aP primary schedule versus the standard aP-only schedule.

The Kids researchers granted $5 million to prevent RHD across Pacific

A team led by Dr Joseph Kado from the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, and The University of Western Australia (UWA) has been awarded $5 million by the Federal Government in a major push to prevent rheumatic heart disease across the Pacific.

Respiratory Illnesses

Coming up in 2021 We have a a study to suit every age range in 2021! From babies at just six weeks for the FluBub Study, through to teenagers in

Meningococcal Disease

MenABCWY QUINTET Study Meningococcal disease is a rare but serious disease that can result in death if not recognised and treated quickly. There are

The PRIME Study

Vaccine Trials Group with Sir Charles Gairdner Hospital is conducting a trial of a vaccine against Clostridium difficile infection (CDI) in at-risk individuals.

Moorditj Marp (Strong Skin) Storybook Evaluation Project

Through co-design with community members, we hope to better understand the strengths and effectiveness of community-driven health promotion resources.

RSV Study for Pregnant Mums

The study aims to determine whether an RSV vaccine given to pregnant women during the third trimester can protect newborn babies from RSV infections.

PAEDS - Paediatric Active Enhanced Surveillance

The PAEDS Study monitors childhood conditions of public health importance that are difficult to effectively capture through other surveillance mechanisms.

AusVaxSafety (previously FAST)

The aim of the study is the early identification of problems with the current flu vaccines, and providing parents and professionals with up to date information.

The Western Australian Influenza Vaccine Effectiveness Study (WAIVE)

The main objectives were to evaluate effectiveness of the annual flu vaccine in young children, and the burden of flu on young children and their families.