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The first ever comprehensive study to estimate the prevalence of otitis media (OM) in Papua New Guinea (PNG) has revealed some of the world’s highest rates of childhood middle ear disease.
A unique study purposely giving participants Streptococcus pyogenes (Strep A) to learn how much penicillin it takes to prevent infection has found the amount needed is much lower than previously thought – a discovery that will transform thinking on treatment for people living with rheumatic heart disease (RHD).
A new study underway at the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, is deliberately infecting tonsils with Strep A in the laboratory to test a range of potential vaccine candidates.
National research led by the Wesfarmers Centre of Vaccines and Infectious Diseases, based at The Kids Research Institute Australia, has secured more than $3.4 million to assess the epidemiology of respiratory syncytial virus (RSV) throughout the country and optimise Australia’s immunisation strategy.
Wesfarmers Centre of Vaccines and Infectious Diseases researchers Dr Janessa Pickering and Dr August Mikucki travelled to Broome last week for the official launch of the long-awaited Missing Piece story books.
Perth investigators involved in a major global trial have launched an innovative Cultural Information Hub to maximise cultural safety for Aboriginal and/or Torres Strait Islander patients participating in research.
10,000 families participating in research by The Kids Research Institute Australia have demonstrated the effectiveness of a simple text message for increasing the number of children receiving their vaccinations on time.
Many parents may be feeling anxious and confused about what COVID-19 means for pregnant women, babies and children.
This paper presents a comprehensive cardiac safety framework for early clinical development of Streptococcus pyogenes (Group A Streptococcus) vaccines, endorsed by the Strep A Vaccine Global Consortium and the Australian Strep A Vaccine Initiative. Given historical concerns about vaccine-associated acute rheumatic fever, we have established standardized echocardiography protocols integrated with clinical assessment for monitoring cardiac safety in early-phase vaccine trials.
During 2013–2017, the mortality rate ratio for rheumatic heart disease among Indigenous versus non-Indigenous persons in Australia was 15.9, reflecting health inequity. Using excess mortality methods, we found that deaths associated with rheumatic heart disease among Indigenous Australians were probably substantially undercounted, affecting accuracy of calculations based solely on Australian Bureau of Statistics data.