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Research

Facial asymmetry in parents of children on the autism spectrum

Greater facial asymmetry has been consistently found in children with autism spectrum disorder (ASD) relative to children without ASD. There is substantial evidence that both facial structure and the recurrence of ASD diagnosis are highly heritable within a nuclear family. Furthermore, sub-clinical levels of autistic-like behavioural characteristics have also been reported in first-degree relatives of individuals with ASD, commonly known as the 'broad autism phenotype'.

Research

Performance of the Autism Observation Scale for Infants with community-ascertained infants showing early signs of autism

We investigated whether a commonly used research assessment - the Autism Observation Scale for Infants (AOSI) - accurately measures autism behaviours among infants showing early signs of autism identified within the community. The AOSI is often included in studies tracking the development of infants at increased likelihood of autism, such as the infant siblings of diagnosed children. However, the suitability of this measure has not previously been tested with community-referred infants.

Research

Effect of Preemptive Intervention on Developmental Outcomes Among Infants Showing Early Signs of Autism: A Randomized Clinical Trial of Outcomes to Diagnosis

Intervention for individuals with autism spectrum disorder (ASD) typically commences after diagnosis. No trial of an intervention administered to infants before diagnosis has shown an effect on diagnostic outcomes to date.

Research

A role for affectivity in rapid facial mimicry: An electromyographic study

Using a novel methodological approach, these findings provide evidence for the contention that affective processing underlies rapid facial mimicry reactions

Research

The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis

These results indicate a coordination of central and peripheral oxytocin release after stress and after intranasal administration

Research

Early autism symptoms in infants with tuberous sclerosis complex

We examined early signs of ASD in infants wit tuberous sclerosis complex, approximately 50% of whom will meet criteria for ASD by age 3.

Research

Hypermasculinised facial morphology in boys and girls with Autism Spectrum Disorder and its association with symptomatology

This is the first study demonstrating facial hypermasculinisation in ASD and its relationship to social-communication difficulties in prepubescent children

Research

Brief social attention bias modification for children with autism spectrum disorder

Social attention can be acutely modified in children with ASD, with an increased tendency to orient attention toward faces after brief social attention training