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3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) riskGenome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified variants lie in non-coding regions, limiting the identification of mechanisms that contribute to autoimmune disease progression.
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Clinical and demographic risk factors associated with mortality during early adulthood in a population-based cohort of childhood-onset Type 1 diabetesThis paper reports calculated standardized mortality ratios in patients with Type 1 diabetes, and assesses the association between poor management of...
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Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: An international comparisonImproving glycaemic control in people with Type 1 diabetes is known to reduce complications.
Research
Type 1 DiabetesA lifelong auto-immune condition that can affect anyone, but is most commonly diagnosed in childhood.
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Navigating the teenage years with type 1 diabetesThe teenage years can be a challenging time for families, a period made even more difficult if a child has type 1 diabetes.
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30% of children at risk of future heart diseaseAlmost 30% of 14-year-old Australian children fall within a group identified as being at future increased risk of heart disease, type 2 diabetes or stroke
Research
The Challenges of Being Physically Active: A Qualitative Study of Young People With Type 1 Diabetes and Their ParentsBenefits of physical activity are well recognized for youth with type 1 diabetes mellitus (T1DM), but being active is challenging. In this study, we aimed to investigate the challenges experienced by adolescents, their parents and young adults with T1DM when they are physically active.
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Lipid profile is associated with treatment regimen in a large cohort of children and adolescents with Type 1 diabetes mellitusOur results indicate that pump therapy is associated with a better lipid profile
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Role of HLA-DQ typing and anti-tissue transglutaminase antibody titers in diagnosing celiac disease without duodenal biopsy in type 1 diabetesHLA-DQ typing is not cost effective as a first-line screening test for CD in T1D patients because of over-representation of CD permissive HLA alleles in this group
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Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA StudyFindings provide novel insight into the composition of the gut virome during pregnancy and demonstrate a distinct profile of viruses in women with type 1 diabetes