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3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) riskGenome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified variants lie in non-coding regions, limiting the identification of mechanisms that contribute to autoimmune disease progression.
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Real-world outcomes of insulin pump compared to injection therapy in a population-based sample of children with type 1 diabetesPatients using insulin pump therapy had a better long-term glycemic control relative to the matched injection therapy cohort
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Clinical and demographic risk factors associated with mortality during early adulthood in a population-based cohort of childhood-onset Type 1 diabetesThis paper reports calculated standardized mortality ratios in patients with Type 1 diabetes, and assesses the association between poor management of...
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Type 1 DiabetesA lifelong auto-immune condition that can affect anyone, but is most commonly diagnosed in childhood.
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Navigating the teenage years with type 1 diabetesThe teenage years can be a challenging time for families, a period made even more difficult if a child has type 1 diabetes.
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High hopes for preventing lowsResearchers led by the team at the Children’s Diabetes Centre at The Kids have taken a key step to a fully automated closed-loop insulin delivery system.
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Reproducibility of plasma glucose responses to moderate-intensity exercise in individuals with type 1 diabetesTo examine the within-person variability in plasma glucose responses to moderate-intensity morning exercise in young individuals with type 1 diabetes after overnight fasting and under basal insulin conditions.
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The Challenges of Being Physically Active: A Qualitative Study of Young People With Type 1 Diabetes and Their ParentsBenefits of physical activity are well recognized for youth with type 1 diabetes mellitus (T1DM), but being active is challenging. In this study, we aimed to investigate the challenges experienced by adolescents, their parents and young adults with T1DM when they are physically active.
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Selective attention to threat, anxiety and glycaemic management in adolescents with type 1 diabetesPrevious research has established that adolescents with type 1 diabetes (T1D) experience more anxiety symptoms than their healthy peers and are also more likely to develop an anxiety disorder. Research in cognitive psychology has found that selective attention favouring the processing of threatening information causally contributes to elevated levels of anxiety; however, this process has not been investigated in the context of T1D.
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The utility of continuous glucose monitoring systems in the management of children with persistent hypoglycaemiaGlucose monitoring is vital in children with persistent hypoglycaemia to reduce the risk of adverse neuro-behavioural outcomes; especially in children with hyperinsulinism. The role of continuous glucose monitoring (CGM) systems in monitoring glucose levels in this cohort is limited.