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Effectiveness of current digital cognitive behavioural therapy for insomnia interventions for adolescents with insomnia symptoms: A systematic review and meta-analysisSleep problems occur in up to 20%-45% of adolescents. This systematic review and meta-analysis examined the effectiveness of digital sleep interventions, based on cognitive behavioural therapy for insomnia, for adolescents with insomnia symptoms. The objective was to synthesise and quantify, through meta-analyses, changes in sleep following completion of a digital sleep-based intervention.
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Transcriptomic analysis of primary nasal epithelial cells reveals altered interferon signalling in preterm birth survivors at one year of ageMany survivors of preterm birth (<37 weeks gestation) have lifelong respiratory deficits, the drivers of which remain unknown. Influencers of pathophysiological outcomes are often detectable at the gene level and pinpointing these differences can help guide targeted research and interventions. This study provides the first transcriptomic analysis of primary nasal airway epithelial cells in survivors of preterm birth at approximately 1 year of age.
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Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort studyThere is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments.
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The ventilatory response to hypoxia is blunted in some preterm infants during the second year of lifePreterm birth and subsequent neonatal ventilatory treatment disrupts development of the hypoxic ventilatory response (HVR). An attenuated HVR has been identified in preterm neonates, however it is unknown whether the attenuation persists into the second year of life.
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The effect of aquatic high-intensity interval training on aerobic performance, strength and body composition in a non-athletic populationIn a non-athletic population, aquatic-high-intensity interval training was safe and may have improved aerobic performance and lower limb strength
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The association between Staphylococcus aureus and subsequent bronchiectasis in children with cystic fibrosisDe novo S. aureus acquisition at age 3 is associated with later bronchiectasis and FEF25-75 in children with CF
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Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early lifeIntra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life
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Preschool Multiple-Breath Washout Testing. An Official American Thoracic Society Technical StatementConsensus recommendations are outlined to direct preschool device design, test performance, and data analysis for the MBW technique
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Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosisThe lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection
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Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for CaucasiansThis is the largest collection of normative T LCO data, and the first global reference values available for T LCO.