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Happy Parenting Program

The Happy Parenting Program is investigating new ways to provide support to parents with young children from an early age.

The Dental Screening Study

Assessing a dental photographic method as an alternative dental screening method.

Machine Learning Approaches for Anatomical Measurement in Fetal Ultrasound Images

This study is investigating whether a machine learning based approach can be used to improve fetal brain anatomy measurement for learning development studies.

Sub-projects

As well as ORIGINS long-term core research, there are a number of clinical trials, early interventions and shorter-term research studies that sit within ORIGINS. Known as sub-projects, these studies look at multiple aspects of child and family health and development.

News & Events

ORIGINS is pleased to announce the 2024 recipient of its inaugural PhD Student Award

Miss Braddon will be awarded with $15,000 to go towards her research project, DreamStart

Be involved

By participating in ORIGINS, you are contributing to one of the largest and most comprehensive birth cohort studies ever.

Benefits for ORIGINS Families

ORIGINS is an interventional cohort study, meaning participants receive timely feedback and an action plan to address any potential abnormalities.

Research

PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensity

A significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.

Research

The feasibility of a digital health approach to facilitate remote dental screening among preschool children during COVID-19 and social restrictions

Tele-dentistry can be useful to facilitate screening of children, especially those living in rural and remote communities, and during the COVID-19 pandemic. This study evaluated the feasibility of tele-dental screening for the identification of early childhood caries (ECC) in preschoolers using an app operated by their parents with remote review by oral-health therapists.

Research

Earth dreams: Reimagining ARPA for health of people, places and planet

Bold new approaches are urgently needed to overcome global health challenges. The proposed Advanced Research Projects Agency for Health (ARPA-H) is intended to provide rapid health breakthroughs.