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Developmental vitamin D deficiency increases foetal exposure to testosteroneAutism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypothesis links excessive sex-steroid exposure during foetal life with the behavioural differences observed in ASD. However, the reason why sex steroid exposure may be excessive remains unclear. Epidemiological studies have identified several environmental risk factors associated with ASD, including developmental vitamin D (DVD) deficiency.
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Developmental Relationship-Based Interventions for Autistic ChildrenAndrew Videos Whitehouse Watch and listen to Andrew PhD Deputy Director (Research); Angela Wright Bennett Professor of Autism Research at The Kids
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Caregiver-Mediated Early Support Program Delivered Online Versus Care-as-Usual for Infants at Elevated Familial Likelihood for AutismLiL' STEPS (Language development & Intervention Lab's SupporTing Early social-communication and language by Promoting caregiver Sensitive responsiveness) is a novel, manualized, caregiver-mediated early support program developed in India and delivered online for infants at elevated familial likelihood for autism. The program has been found to be feasible and acceptable. The preliminary efficacy of the LiL' STEPS program, which remains to be evaluated, was assessed in this study using a feasibility randomized controlled trial design.
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Genome-wide association meta-analysis of childhood ADHD symptoms and diagnosis identifies new loci and potential effector genesWe performed a genome-wide association meta-analysis of 290,134 attention-deficit/hyperactivity disorder symptom measures of 70,953 unique individuals from multiple raters, ages and instruments.
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Maternal Conditions and Perinatal Characteristics Associated with Autism Spectrum Disorder and Intellectual DisabilityFindings show that indicators of a poor intrauterine environment are associated with an elevated risk of ID, while for ASD, and particularly ASD without ID,...
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Parent–child book reading across early childhood and child vocabulary in the early school yearsThe current study investigated the extent to which low levels of joint attention in infancy and parent-child book reading across early childhood increase the...
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Factors relating to pregnancy and birth and the risk of childhood brain tumors: Results from an Australian case-control studyChildhood brain tumors (CBT) are the leading cause of cancer death in children, yet their causes are largely known. This study investigated the association...
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Young Children in Indonesia's Low-income Rural Communities: How are they doing and what do they need?This chapter describes the development of young children in a sample of poor rural communities across Indonesia.
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Environmental Risk Factors by Gender Associated With Attention-Deficit/Hyperactivity DisorderOur study investigates the maternal, pregnancy, and newborn risk factors by gender for children prescribed stimulant medication for treatment of ADHD in WA.
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What does the nature of the MECP2 mutation tell us about parental origin and recurrence risk in Rett syndrome?The MECP2 mutations occurring in the severe neurological disorder Rett syndrome are predominantly de novo, with rare familial cases. The aims of this study...