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Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconusCentral corneal thickness (CCT) is associated with eye conditions including keratoconus and glaucoma.
Research
Admissions in Children with Down Syndrome: Experience of a Population-Based Cohort Followed from BirthThis study describes patterns of hospitalisations for children and young people with Down syndrome in Western Australia.
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Lung function in African infants: A pilot studyInfant lung function (ILF) testing may provide useful information about lung growth and susceptibility to respiratory disease.
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Modelling the seasonality of respiratory syncytial virus in young childrenThe transmission dynamics of RSV infection among young children are still poorly understood and mathematical modelling can be used to better understand...
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The Western Australian family connections genealogical project: Detection of familial occurrences of single gene and chromosomal DisordersThis study utilised a Western Australian (WA) genealogical database for the identification of single gene and chromosome disorders among families.
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Exposure to household painting and floor treatments, and parental occupational paint exposure and risk of childhood brain tumorsThis study investigated whether household exposure to paints and floor treatments and parental occupational painting were associated with CBT risk...
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Prevention of rheumatic fever and heart disease: Nepalese experienceHistorically, many young people suffered severe valvular disease and died awaiting heart valve replacement.
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Environmental determinants of islet autoimmunity (ENDIA): a pregnancy to early life cohort study in children at-risk of type 1 diabetesThese observations suggest factors in the modern environment promote pancreatic islet autoimmunity and destruction of insulin-producing beta cells.
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Impact of CD14 promoter variants on measles vaccine responses and vaccine failure in children from Australia and MozambiqueHost genetics are likely to play a crucial role, particularly variants that alter key innate immune response genes.
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Optimal conditions required for influenza A infection-enhanced cross-priming of CD8+ T cells specific to cell-associated antigensOur group has recently shown that influenza A virus (IAV) infection of allogeneic cells lead to enhanced cross-priming of TCD8+ specific to cellular antigens.