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Symptomatic viral infection is associated with impaired response to treatment in children with acute asthmaThe objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.
Research
Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specificChronic innocuous aeroallergen exposure attenuates CD4+ T cell-mediated airways hyperresponsiveness in mice; however, the mechanism(s) remain unclear
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Bronchial brushings for investigating airway inflammation and remodellingAsthma is the commonest medical cause for hospital admission for children in Australia, affects more than 300 million people worldwide, and is incurable...
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Neonatal immune function and inflammatory illnesses in later life: lessons to be learnt from the developing world?With the emergence of allergic and autoimmune diseases in populations that have started to transit to a western lifestyle, there has been an increasing...
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House dust mite allergens in asthma and allergyIgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against
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Early immunological influences on asthma development: opportunities for early interventionEarly immunological influences on asthma development: opportunities for early intervention
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Investigations into the role of ST2 in acute asthma in childrenThis study investigated the potential role of ST2 in children with acute asthma.
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Acute viral bronchiolitis in infants and young childrenThis project aims to plug this knowledge gap, and to open up new opportunities for development of better treatments targeted specifically at infants.
News & Events
Census data reveals stark gap in asthma risk for inner and outer city kidsChildren who live in the outer suburbs of Australia’s four biggest cities are twice as likely to have asthma as those living in inner city areas, according to a new study based on health data captured in the last Australian Census.
Research
Elucidation of pathways driving asthma pathogenesis: Development of a systems-level analytic strategyWhereas asthma was rare in the late 1800s and early 1900s, the marked increase in its incidence and prevalence since the 1960s points to substantial gene ×...