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There is variability in the attainment of developmental milestones in the CDKL5 disorderIndividuals with the CDKL5 disorder have been described as having severely impaired development.
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Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukaemiaSeveral studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL).
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Aberrant expression of aldehyde dehydrogenase 1A (ALDH1A) subfamily genes in acute lymphoblastic leukaemia is a common feature of T-lineage tumoursThe class 1A aldehyde dehydrogenase (ALDH1A) subfamily of genes encode enzymes that function at the apex of the retinoic acid (RA) signalling pathway.
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Developing a Model to Account for Attrition Bias in a Longitudinal CohortOur objective was to develop a method that could be applied in a longitudinal cohort study to account for attrition bias in an investigation of exclusive...
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Morbidity due to acute lower respiratory infection in children with birth defects: A total population-based linked data studyChildren with birth defects experience higher rates of hospitalisation for ALRIs before age 2 years than children with no birth defects.
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How Accurate Are International Classification of Diseases-10 Diagnosis Codes in Detecting Influenza and Pertussis Hospitalizations in Children?Influenza diagnosis codes had high specificity (98.6%) and modest positive predictive value (PPV; 84.1%) and sensitivity (86.1%) for a laboratory-confirmed...
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Neonatal complications in public and private patients: A retrospective cohort studyDespite the rates of low Apgar scores being higher in public patients, the rates of special care admission were lower.
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Maternal Alcohol Use and Sudden Infant Death Syndrome and Infant Mortality Excluding SIDSThe highest risk of SIDS occurred when a maternal alcohol diagnosis was recorded during pregnancy or within 1 year postpregnancy.
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Pleurodesis outcome in malignant pleural mesotheliomaSurgical pleurodesis showed no advantages over bedside pleurodesis in efficacy, patient survival or total time spent in hospital from procedure till death.
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Hospitalisation for bronchiolitis in infants is more common after elective caesarean deliveryThe authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by...