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Correlation of ultra-low dose chest CT findings with physiologic measures of asbestosisThis study aimed to determine the relationship between ULDCT-ILD and measures of pulmonary function in an asbestos-exposed population.
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Data linkage in an established longitudinal cohort: The Western Australian Pregnancy Cohort (Raine) StudyA healthy diet was consistently associated with higher academic performance
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Seasonal trivalent influenza vaccination during pregnancy and the incidence of stillbirth: Population-based retrospective cohort studyAlthough antenatal influenza vaccination is an important public health intervention for preventing serious infection in pregnant women and newborns, reported...
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Progressive ventilation inhomogeneity in infants with cystic fibrosis after pulmonary infectionThis study aimed to determine how pulmonary inflammation & infection impacts on ventilation distribution throughout early life in people with cystic fibrosis.
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Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomesResults from this linked population study suggests that there are differences in maternal infection by virus type and support the provision of seasonal vaccines
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Childhood Hospitalisation with Infection and Cardiovascular Disease in Early-Mid Adulthood: A Longitudinal Population-Based StudyWe investigated whether childhood infection-related hospitalisation (IRH, a marker of severity) was associated with subsequent adult CVD hospitalisation.
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Longitudinal analysis of respiratory outcomes among bauxite exposed workers in western AustraliaThis study investigated any associations between cumulative bauxite exposure and respiratory symptoms.
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Higher maternal bread and thiamine intakes are associated with increased infant allergic diseaseA mother's diet during pregnancy may influence her infant's immune development. However, as potential interactions between components of our dietary intakes can make any nutritional analysis complex, here we took a multi-component dietary analysis approach.
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Zika Virus Changes Methylation of Genes Involved in Immune Response and Neural Development in Brazilian Babies Born With Congenital MicrocephalyThe recent increase in babies born with brain and eye malformations in Brazil is associated with Zika virus (ZIKV) infection in utero. ZIKV alters host DNA methylation in vitro. Using genome-wide DNA methylation profiling we compared 18 babies born with congenital ZIKV microcephaly with 20 controls. We found ZIKV-associated alteration of host methylation patterns, notably at RABGAP1L which is important in brain development, at viral host immunity genes MX1 and ISG15, and in an epigenetic module containing the causal microcephaly gene MCPH1. Our data support the hypothesis that clinical signs of congenital ZIKV are associated with changes in DNA methylation.
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The effect of functioning on Quality of Life Inventory-Disability measured quality of life is not mediated or moderated by parental psychological distressThe measurement of quality of life (QOL) in children with intellectual disability often relies upon proxy report via caregivers. The current study investigated whether caregiver psychological distress mediates or moderates the effects of impairment on their ratings of QOL in children with intellectual disability.