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Research

Social impairments in autism spectrum disorder are related to maternal immune history profile

this study is the first to show an association between immune activation history in the mother and increased ASD symptom severity in children with ASD

Research

Does perinatal exposure to exogenous oxytocin influence child behavioural problems and autistic-like behaviours to 20 years of age

This study is the first to investigate longitudinal mental health outcomes associated with the use of oxytocin-based medications during labour

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Reduced heart rate variability in adults with autism spectrum disorder

Our data suggest an overall dysregulation in resting autonomic activity in adults with autism spectrum disorder

Research

The Comprehensive Autistic Trait Inventory (CATI): development and validation of a new measure of autistic traits in the general population

Traits and characteristics qualitatively similar to those seen in diagnosed autism spectrum disorder can be found to varying degrees in the general population. To measure these traits and facilitate their use in autism research, several questionnaires have been developed that provide broad measures of autistic traits [e.g. Autism-Spectrum Quotient (AQ), Broad Autism Phenotype Questionnaire (BAPQ)]. However, since their development, our understanding of autism has grown considerably, and it is arguable that existing measures do not provide an ideal representation of the trait dimensions currently associated with autism. Our aim was to create a new measure of autistic traits that reflects our current understanding of autism, the Comprehensive Autism Trait Inventory (CATI).

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Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms

Differences in regional GMV are discernible at an early stage of UHR and may be specific to individuals who have APS and psychopathology at follow-up

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Evidence for shared deficits in identifying emotions from faces and from voices in autism spectrum disorders and specific language impairment

While autism spectrum disorder (ASD) and specific language impairment (SLI) have traditionally been conceptualized as distinct disorders, recent findings...

Research

Prenatal testosterone exposure is related to sexually dimorphic facial morphology in adulthood

Prenatal testosterone may have a powerful masculinizing effect on postnatal physical characteristics.

Research

Beyond the hype and hope: Critical considerations for intranasal oxytocin research in autism spectrum disorder

In this review, we comprehensively evaluate the rationale for oxytocin as a therapeutic, evaluating evidence from various various sources.

Research

Randomised controlled trial of an iPad based early intervention for autism: TOBY playpad study protocol

This trial will determine the effectiveness of the TOBY App as a therapeutic complement to other early interventions children with ASD receive

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Age invariance in rapid facial affective reactions to emotionally valenced stimuli

Rapid facial reactions to emotional stimuli are intact in late adulthood, even in response to stimuli that activate more automatic and implicit forms of emotion processing