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Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case seriesWe describe a series of 6 cases where adoption of a low carbohydrate diet in children impacted growth and cardiovascular risk factors with potential long-term sequelae.
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Motor abnormalities in Rett SyndromeFor most individuals, there is initial developmental progress followed by regression at around 6–30 months. The classic signs of RTT then become apparent.
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Reproducibility of the plasma glucose response to moderate-intensity exercise in adolescents with Type 1 diabetesThe plasma glucose response to moderate-intensity exercise can be reproducible in adolescents with Type 1 diabetes
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Clinical, research, and public health implications of poor measurement of Vitamin D statusNew initiatives to develop a standard reference method and the assignment of "true" values to samples provide a solution to these problems.
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Prevalence of celiac disease in 52,721 youth with type 1diabetes: International comparison across three continentsTim Jones MBBS DCH FRACP MD Co-head, Diabetes and Obesity Research Co-head, Diabetes and Obesity Research Areas of research expertise: Diabetes
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Unexpected Management Behaviors in Adolescents With Type 1 Diabetes Using Sensor-Augmented Pump TherapyConstant exposure to real-time data can lead to unsafe management responses in adolescents with the behavior influenced by trust or mistrust in the system
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The Importance of the Hawthorne Effect on Psychological Outcomes Unveiled in a Randomized Controlled Trial of Diabetes TechnologyThe objective of this communication is to highlight the Hawthorne effect on psychobehavioral measures and the importance of a control group in clinical research, particularly for diabetes technologies
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A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetesThe Pankowska Equation resulted in reduced postprandial hyperglycaemia at the expense of an increase in hypoglycaemia
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Copeptin Kinetics and Its Relationship to Osmolality During Rehydration for Diabetic Ketoacidosis in ChildrenCopeptin is a surrogate marker for arginine vasopressin (AVP) release in response to hyperosmolal stimuli such as diabetic ketoacidosis (DKA). The objective of this work is to characterize kinetics of copeptin and osmolality, and their dynamic relationship during rehydration and insulin therapy in children with type 1 diabetes (T1D) and DKA.
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DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studiesDNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely unknown. More insight into this relationship at younger ages may have implications for future prevention of obesity and its related traits. We examined whether DNA methylation in cord blood and whole blood in childhood and adolescence was associated with BMI in the age range from 2 to 18 years using both cross-sectional and longitudinal models.