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Research

Comment on "Drug discovery: Turning the titanic"

We propose that the molecular and cellular events that govern a resolving, rather than an evolving, disease may reveal new druggable pathways.

Research

Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age

This paper examines whether a Vitamin D deficiency during pregnancy affects the child's lung function predisposition towards lung disease such as asthma.

Research

Changes in risk factors for preterm birth in Western Australia 1984-2006

Marked increases in maternal age and primiparous births were observed. A four-fold increase in the rates of pre-existing medical complications over time...

Research

Brief Report: Do the Nature of Communication Impairments in Autism Spectrum Disorders Relate to the Broader Autism Phenotype in Parents?

This research explored the relationship between the broader autism phenotype (BAP) among parents, an index of genetic liability for ASD, and proband...

Research

Short report: Care for children and adolescents with diabetes in Australia and New Zealand: Have we achieved the defined goals?

In 2010, the Australasian Paediatric Endocrinology Group formed a national Children's Diabetes Network that represented clinical teams managing over 95% of...

Research

Methodological approach to exploring change in the Australia Early Development Instrument (AEDI): The estimation of a critical difference

This report provides the technical details for the methodology calculated to determine "how big" a difference in the AEDI results between 2009 and 2012 is...

Research

The influence of moving walls on respiratory aerosol deposition modelling

This work initially examines particle deposition in a Weibull-type geometry, comparing traditional computational fluid dynamics approaches with a novel...

Research

Innate affairs of allergens

Activation of receptors of the innate immune system is a critical step in the initiation of immune responses.

Research

Prospective associations between sugar-sweetened beverage intakes and cardiometabolic risk factors in adolescents

We tested the hypothesis that higher SSB intakes are associated with increases in cardiometabolic risk factors between 14 and 17 y of age.

Research

Cancer-related mortality in people with mental illness

There is a 30% higher case fatality rate from cancer in psychiatric patients even though their incidence of cancer is no greater than in the general population.