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Detecting genotyping error using measures of degree of Hardy-Weinberg disequilibrium - art. no. 5Tests for Hardy-Weinberg equilibrium (HWE) have been used to detect genotyping error, but those tests have low power unless the sample size is very large.
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Confirmation of childhood acute lymphoblastic leukemia Variants, ARID5B and IKZF1, and interaction with parental environmental exposuresThe polygenic nature of childhood ALL predisposition together with the timing of environmental triggers may hold vital clues for disease etiology.
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Investigating the long-term impact of a childhood sun-exposure intervention, with a focus on eye health: protocol for the Kidskin-Young Adult Myopia StudyA follow-up of Kidskin Study participants provides an opportunity to investigate the associations between a childhood sun-exposure intervention and potentially related conditions in adulthood
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Risk of cancer among children with birth defects: A novel approachThis novel approach aimed to prevent inflated hazard ratios arising from reverse causation, and allow identification of associations beyond those already...
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Linked data research: a valuable tool in the ART fieldThis letter to the editor endorses data linkage studies and cites their potential value over other types of epidemiological studies within the field of...
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Risk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticidesRisk of childhood acute lymphoblastic leukaemia following parental occupational exposure to pesticides.
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Exposure to professional pest control treatments and the risk of childhood acute lymphoblastic leukemiaPrevious studies suggest that exposure to pesticides increases the risk of childhood acute lymphoblastic leukemia
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Participation in paediatric cancer studies: Timing and approach to recruitmentIn this sub-study, we aimed to investigate factors that may have influenced study participation and completeness of survey completion.
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Dr Sébastien MalingeLaboratory Head, Translational Genomics in Leukaemia, Ursula Kees Fellow (CCRF), Cancer Council WA Fellow (CCWA), Senior Research Fellow (UWA), University Associate (Curtin)
Research
Folate pathway gene polymorphisms, maternal folic acid use, and risk of childhood acute lymphoblastic leukaemiaSeveral studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL).