Search
Research
Impaired T cell proliferation by ex vivo BET-inhibition impedes adoptive immunotherapy in a murine melanoma modelWe established a pipeline to assess the effects of epigenetic modifiers on CD8+ T cell proliferation, differentiation, and efficacy in a preclinical melanoma model
Research
Using pneumococcal carriage studies to monitor vaccine impact in low- and middle-income countriesWe review the role of pneumococcal carriage studies for the evaluation of PCVs in LMICs and discuss optimal methods for conducting these studies
Research
A framework for the management of the pediatric airwayA simple, time critical, and pediatric-specific airway management approach will help to reduce airway-related pediatric morbidity and mortality
Research
Early life determinants of health: Invest early to break the cycle of long-term disadvantage in neurodevelopmental disordersThis chapter discusses the importance of investment in early life determinants of health to break the cycle of long-term disadvantage. This chapter addresses these issues while focussing on neurodevelopmental disorders and their related mental health concerns as the targets at the centre of a biopsychosocial transformation of the health system.
Research
Duration of general anaesthetic exposure in early childhood and long-term language and cognitive abilityAnaesthetic dose causing toxicity in animals has been evaluated, but the relationship between duration of VA exposure and development in children remains vague.
Research
Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical ResearchWe outline three scenarios from across the health spectrum where issues with health informatics are exemplified.
Research
Family Involvement in a Whole-School Bullying Intervention: Mothers’ and Fathers’ Communication and Influence with ChildrenThese results highlight the importance of working with both male and female caregivers when addressing children’s bullying behaviour.
Research
A randomized controlled evaluation of a secondary school mindfulness program for early adolescents: Do we have the recipe right yet?Further research is required to identify the optimal age, content and length of mindfulness programs for adolescents in universal prevention settings.
Research
Effect of obesity on neonatal hypoglycaemia in mothers with gestational diabetes: A comparative studyTo determine the influence of obesity on neonatal hypoglycaemia among infants born to gestational diabetes mellitus mothers.
Research
Puberty suppression in transgender children and adolescentsWe review the available empirical evidence on the cognitive, physical, and surgical implications of puberty suppression in gender-incongruent children and adolescents