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Research

Toll-like receptor 7 and 8 polymorphisms: associations with functional effects and cellular and antibody responses to measles virus and vaccine

Successful defence against viral pathogens requires the rapid recognition of virus-specific "danger signals" and the activation of both innate and adaptive...

Research

Tertiary paediatric refugee health clinic in Western Australia: Analysis of the first 1026 children

The aim of this study is to describe the epidemiology of common conditions in resettled paediatric refugees attending a tertiary multidisciplinary RHC.

Research

Peptides targeting the mitogen-activated protein kinase pathway (JNK/JUN) fail to reduce infarct volume after permanent MCAO in sprague dawley rats

In this study we have assessed the ability of two TAT-fused peptides to reduce infarct volume and improve functional outcome following permanent ischaemia.

Research

Symptomatic viral infection is associated with impaired response to treatment in children with acute asthma

The objective of this study was to examine the influence of viral respiratory infection (VRI) on treatment response in acute asthma in children.

Research

Kawasaki disease, childhood allergy and the hygiene hypothesis

Kawasaki disease is characterized by increased inflammation

Research

Unpacking the complex nature of the autism epidemic

This paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.

Research

Awareness and impact of the ‘Bubblewrap’ advertising campaign among Aboriginal smokers in Western Australia

Antismoking mass media campaigns have been shown to reduce smoking prevalence in the mainstream community.

Research

Antifungal therapy in infants and children with proven, probable or suspected invasive fungal infections

This review aims to systematically identify and summarise the effects of different antifungal therapies in children with proven, probable or suspected...

Research

Early immunological influences on asthma development: opportunities for early intervention

Early immunological influences on asthma development: opportunities for early intervention

Research

Increased longevity and the comorbidities associated with intellectual and developmental disability

The contributors, all world experts in their fields, also discuss what we can learn from the presence of co-morbidities.