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Research

An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins

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Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average.

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Randomized controlled trial of early regular egg intake to prevent egg allergy

We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema.

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Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease.

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Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown

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Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

In December 2016, a panel of experts was convened by the International Scientific Association for Probiotics an Prebiotics to review the scope of prebiotic.

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Patterns of sedentary time and ambulatory physical activity in a Danish population of girls and women with Rett syndrome

We aimed to: (1) describe the patterns of sedentary time and daily steps and (2) identify the association of individual and environmental characteristitics.

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Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder have an atypical pattern of crying

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The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function.

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Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteins

Phylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited