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Clinician-rated quality of video otoscopy recordings and still images for the asynchronous assessment of middle-ear disease

Video otoscopy plays an important role in improving access to ear health services. This study investigated the clinician-rated quality of video otoscopy recordings and still images, and compared their suitability for asynchronous diagnosis of middle-ear disease. Two hundred and eighty video otoscopy image-recording pairs were collected from 150 children (aged six months to 15 years) by an ear, nose, and throat (ENT) specialist, audiologists, and trained research assistants, and independently rated by an audiologist and ENT surgeon.

Changes in airway inflammation with pseudomonas eradication in early cystic fibrosis

Neutrophil elastase is a significant risk factor for structural lung disease in cystic fibrosis, and Pseudomonas aeruginosa airway infection is linked with neutrophilic inflammation and substantial respiratory morbidity. We aimed to evaluate how neutrophil elastase (NE) activity changes after P. aeruginosa eradication and influences early disease outcomes. We assessed participants in the AREST CF cohort between 2000 and 2018 who had P. aeruginosa cultured from their routine annual bronchoalveolar lavage (BAL) fluid and who underwent eradication treatment and a post eradication BAL. Factors associated with persistent P. aeruginosa infection, persistent neutrophilic inflammation following eradication and worse structural lung disease one year post-eradication were evaluated.

The Human Phenotype Ontology in 2021

The Human Phenotype Ontology was launched in 2008 to provide a comprehensive logical standard to describe and computationally analyze phenotypic abnormalities found in human disease. The HPO is now a worldwide standard for phenotype exchange. The HPO has grown steadily since its inception due to considerable contributions from clinical experts and researchers from a diverse range of disciplines. Here, we present recent major extensions of the HPO for neurology, nephrology, immunology, pulmonology, newborn screening, and other areas.

Early childhood researcher a finalist in peak South Australian science awards

A The Kids Research Institute Australia researcher whose PhD studies highlighted the link between screen time exposure and toddlers’ language development has been named a finalist in South Australia’s Science Excellence and Innovation Awards.

Early Years Partnership budget boost welcomed

The Kids Research Institute Australia has welcomed today’s announcement by the Cook Government and Minderoo Foundation of a $34.6 million boost for the Early Years Partnership to achieve better outcomes for children.

The Kids Research Institute Australia to lead ground-breaking child health research in South Australia

The Kids Research Institute Australia's Adelaide facility has been officially opened by South Australian Premier Peter Malinauskas.

It’s a draw! Creative study seeks kids’ drawings to help understand sibling dynamics

Children across Australia aged 4-12 years are being asked to grab their crayons, pencils or pens and create their best drawing of themselves and their siblings in a simple study that will help researchers learn more about sibling relationships.

The Kids researcher joins global program to enhance mental health of bubs

A The Kids Research Institute Australia researcher whose work focuses on the mental health of babies and young children has been chosen from a global field to become one of 20 new Zero to Three Fellows.

Improving development and learning of children in Western Australia

Discover the EYI Research Profile at The Kids' Institute, showcasing innovative child health research and its impact on young lives.

National campaign shows importance of early childhood brain development

A national campaign launched on Channel 7’s Telethon aims to build community understanding of the amazing untapped potential of a baby’s developing brain, through a remarkable animated creature.