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Early-life immune development is a critical factor in predicting the risk of childhood respiratory infections, asthma, and poor vaccine responses. Identifying immune endotypes that predispose children to these conditions could lead to the development of predictive biomarkers and early interventions, potentially improving long-term health outcomes.
Sex-specific developmental differences in brain structure have been documented in older children and adolescents, with females generally showing smaller overall brain volumes and earlier peak ages than males. However, sex differences in gray matter structural development in early childhood are less studied. We characterized sex-specific trajectories of gray matter volume development in children aged 2–8 years.
Few studies have explored associations between indexes incorporating both breastfeeding and complementary feeding and future risk of overweight/obesity. The aim of this study was to explore associations between a previously developed Infant Diet Score (IDS; higher score reflecting better alignment with breastfeeding and complementary feeding guidelines in the first year of life), and the risk of overweight and/or obesity in childhood.
Siblings of individuals with neurodevelopmental conditions have unique experiences and sometimes additional challenges, especially in rural areas where there may be limited access to sibling-specific support services.
This paper provides the conceptual framework for a new review series that bring together the global literature on population approaches to nurturing relational health across the first three years of life. Early relational health is defined as ‘the everyday interactions that happen between children and their carers across the many settings in which they live and grow.
Rhinoviruses (RV) are the most common respiratory viruses globally and a major cause of airway symptoms in children and individuals with asthma. Although more than 170 RV types exist across 3 species (RV-A, RV-B, RV-C), type-specific circulation patterns and age-related prevalence remain poorly defined.
To assess the implementation of the digital version of the Physical Literacy in Children Questionnaire (PL-C Quest) in a primary school environment.
Playgrounds are essential for children's physical, mental, and social development, yet there is a lack of high-quality evaluations of playground interventions in public spaces.
To explore Aboriginal families' experiences of recognising clinical deterioration and raising their concerns within the Paediatric ESCALATION system to identify enablers and barriers to family involvement.
To develop consensus on the priorities for multi-centre, inpatient general paediatrics research in Australia and New Zealand.