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The effects of maternal smoking on early mucosal immunity and sensitization at 12 months of ageIn this study, we examined the effects of maternal smoking as a major adverse exposure in early life, on mucosal immune function and allergen sensitization...
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Catalyst Twenty-Twenty: Post-Traumatic Growth at Scales of Person, Place and PlanetPlanetary health is a broad multidisciplinary effort that attempts to address what has been described as “Anthropocene Syndrome”—the wicked, interrelated challenges of our time. These include, but are not limited to, grotesque biodiversity losses, climate change, environmental degradation, resource depletion, the global burden of non-communicable diseases (NCDs), health inequalities, social injustices, erosion of wisdom and civility, together with the many structural underpinnings of these grand challenges.
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Botulinum toxin and surgical intervention in children and adolescents with cerebral palsy: who, when and why do we treat?This audit aimed to increase understanding of the long-term outcomes of evidence-based medical and surgical interventions to improve gross motor function in children and adolescents with Cerebral Palsy.
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Defining Age-specific Relationships of Respiratory Syncytial Virus and Rhinovirus Species in Hospitalized Children With Acute WheezeAcute wheezing is one of the most common hospital presentations for young children. Respiratory syncytial virus (RSV) and rhinovirus (RV) species A, B and the more recently described species C are implicated in the majority of these presentations. However, the relative importance and age-specificities of these viruses have not been defined.
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World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin DVitamin D is involved in the regulation of the immune system and it may play a role in the development, severity and course of asthma and other allergic...
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Natural environments, nature relatedness and the ecological theater: connecting satellites and sequencing to shinrin-yokuMechanisms-including aerobiological and epigenetic-that might help explain some of the noted positive health outcomes
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Dysregulation of innate immunity in ulcerative colitis patients who fail anti-tumor necrosis factor therapyStudy the innate immune function in ulcerative colitis patients who fail to respond to anti-tumor necrosis factor therapy
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Transforming Life: A Broad View of the Developmental Origins of Health and Disease Concept from an Ecological Justice PerspectiveWith emerging research involving green space, the microbiome, biodiversity and positive psychology, we discuss ecological justice in the dysbiosphere
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Randomized controlled trial of early regular egg intake to prevent egg allergydetermining if regular consumption of egg protein from age 4 to 6 months reduces the risk of IgE mediated allergy in infants with genetic risk, without eczema.
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T-cell activation genes differentially expressed at birth in CD4+ T-cells from children who develop IgE food allergyTo show underlying mechanisms, we examined differences in T-cell gene expression in samples at birth and at 1 year in children with and without IgE allergy.