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Research
Variation in Neonatal Nutrition Practice and Implications: A Survey of Australia and New Zealand Neonatal UnitsSignificant global variation exists in neonatal nutrition practice, including in assigned milk composition values, donor milk usage, fortification regimens, probiotic choice and in methods used to calculate and report nutrition and growth outcomes, making it difficult to synthesize data to inform evidence-based, standardized nutritional care that has potential to improve neonatal outcomes
Research
Exploring genotype-phenotype relationships in the CDKL5 deficiency disorder using an international datasetCharacterized by early-onset seizures, global developmental delay and severe motor deficits, CDKL5 deficiency disorder is caused by pathogenic variants in the cyclin-dependent kinase-like 5 gene. Previous efforts to investigate genotype-phenotype relationships have been limited due to small numbers of recurrent mutations and small cohort sizes. Using data from the International CDKL5 Disorder Database we examined genotype-phenotype relationships for 13 recurrent CDKL5 variants and the previously analyzed historic variant groupings. We have applied the CDKL5 Developmental Score (CDS) and an adapted version of the CDKL5 Clinical Severity Assessment (CCSA), to grade the severity of phenotype and developmental outcomes for 285 individuals with CDKL5 variants.
Research
DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studiesDNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely unknown. More insight into this relationship at younger ages may have implications for future prevention of obesity and its related traits. We examined whether DNA methylation in cord blood and whole blood in childhood and adolescence was associated with BMI in the age range from 2 to 18 years using both cross-sectional and longitudinal models.
Research
Tasmania’s child and family centres building parenting capability: a mixed methods studyThis mixed methods study investigated the impact of Tasmania’s Child and Family Centres on parents’ confidence and competence
Research
Early childhood caries, primary caregiver oral health knowledge and behaviours and associated sociological factors in Australia: a systematic scoping reviewEarly childhood caries disproportionately affects vulnerable groups and remains a leading cause of preventable hospital admissions for Western Australian children. The Western Australia State Oral Health Plan seeks to improve child oral health through universal and targeted health promotion initiatives with primary caregivers.
News & Events
National campaign shows importance of early childhood brain developmentA national campaign launched on Channel 7’s Telethon aims to build community understanding of the amazing untapped potential of a baby’s developing brain, through a remarkable animated creature.
News & Events
InFocus Interview - Megan BellAn InFocus Research Interview with Kirsten Hancock of the Human Capability Team at The Kids Research Institute Australia on multigenerational disadvantage in Australia.
News & Events
New report a catalyst for Midland to lead in collaborative community service deliverywe the people worked with CoLab, a partnership between The Kids and Minderoo Foundation, to investigatethe needs of local families with children aged 0to8
News & Events
Building strong foundations for healthy brain developmentAn InFocus Research Interview with Kirsten Hancock of the Human Capability Team at The Kids Research Institute Australia on multigenerational disadvantage in Australia.
News & Events
Great Southern to benefit from 10 year Early Years InitiativeNew ways to deliver more effective, evidenced-informed child development services will be forged through an innovative community partnership in the Central Great Southern.