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Research

Promoting abstinence from alcohol during pregnancy: Implications from formative research

This research developed messages to promote abstinence from alcohol during pregnancy and identified elements that enhance message persuasiveness.

Research

Patterns and trends in mortality of Western Australian infants, children and young people 1980-2008

This report is the third in a series examining patterns and trends in mortality among Western Australian infants, children and young people, and covers...

Research

Bioenergetic modulation overcomes glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia

Drug-resistant forms of acute lymphoblastic leukaemia (ALL) are a leading cause of death from disease in children.

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Tertiary paediatric hospital health professionals' attitudes to lesbian, gay, bisexual and transgender parents seeking health care for their children

Lesbian, gay, bisexual and transgender parents are often reluctant to disclose their sexual orientation to health professionals for fear of discrimination...

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Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions

To determine whether acute wheezing exacerbations due to HRV-C are associated with increased hospital attendances due to acute respiratory illnesses (ARIs).

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Meeting the needs of young people in hospital

For hospital-based clinicians wishing to establish AYA services, how should they proceed and what might such services look like?

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Transition to secondary school: Expectation versus experience

This study investigated what young people in primary school reported being worried about with their impending move to secondary school, and how their...

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Is the effect of compulsory community treatment

We investigated whether a reduction of preventable deaths from physical disorders was mediated by better access to specialized medical procedures.

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Maternal prebiotic supplementation during pregnancy and lactation modifies the microbiome and short chain fatty acid profile of both mother and infant

Improving maternal gut health in pregnancy and lactation is a potential strategy to improve immune and metabolic health in offspring and curtail the rising rates of inflammatory diseases linked to alterations in gut microbiota. Here, we investigate the effects of a maternal prebiotic supplement (galacto-oligosaccharides and fructo-oligosaccharides), ingested daily from <21 weeks' gestation to six months' post-partum, in a double-blinded, randomised placebo-controlled trial. 

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Maternal Allergic Disease Phenotype and Infant Birth Season Influence the Human Milk Microbiome

Early infancy is a critical period for immune development. In addition to being the primary food source during early infancy, human milk also provides multiple bioactive components that shape the infant gut microbiome and immune system and provides a constant source of exposure to maternal microbiota. Given the potential interplay between allergic diseases and the human microbiome, this study aimed to characterise the milk microbiome of allergic mothers.