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Research
Genetic Manipulation of Group A Streptococcus-Gene Deletion by Allelic ReplacementAn optimized, rapid method for creating markerless isogenic mutations that combines Gibson assembly cloning with a new temperature-sensitive plasmid, pLZts
Research
Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injectionBenzathine penicillin G has been used as monthly deep intramuscular (IM) injections since the 1950s for secondary prevention of acute rheumatic fever and rheumatic heart disease (RHD). Injection frequency and pain are major programmatic barriers for adherence, prompting calls for development of better long-acting penicillin preparations to prevent RHD.
Research
Factors associated with pneumococcal carriage and density in children and adults in Fiji, using four cross-sectional surveysThis study describes predictors of pneumococcal nasopharyngeal carriage and density in Fiji
News & Events
Trans Tasman action to fast track rheumatic fever vaccinePrime Ministers of Australia and New Zealand have agreed to provide $3M to help fast-track the development of a vaccine against rheumatic fever.
News & Events
Investigational vaccine for WA's meningococcal threatPerth researchers have begun a clinical trial of an investigational Meningococcal B vaccine against the most common form of meningococcal disease in W.A.
News & Events
Potential new vaccine for WA's meningococcal threatPerth researchers are trialling a Meningococcal B vaccine that could potentially provide protection
News & Events
Beating the flu bugPerth children are being asked to volunteer for an important national study to test the effectiveness of an influenza vaccine in children.
Research
Public health and economic perspectives on acute rheumatic fever and rheumatic heart diseaseEfforts to eliminate ARF and RHD in Australia over the past decade have so far been unsuccessful, but this can change
Research
Exposure to bile leads to the emergence of adaptive signaling variants in the opportunistic pathogen pseudomonas aeruginosaAdaptive variants of P. aeruginosa that arise following long term bile exposure enables the emergence of ecologically competitive sub-populations
Research
Potential use of Western Australia’s mandatory Midwives Notification System for routinely monitoring antenatal vaccine coverageWe observed low sensitivity and specificity of antenatal vaccination data in the Midwives Notification System