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Research

Intrauterine growth restriction (IUGR) is associated with asthma. Murine models of IUGR have altered airway responsiveness in the absence of any inflammatory exposure. Given that a primary feature of asthma is airway inflammation, IUGR-affected individuals may develop more substantial respiratory impairment if subsequently exposed to an allergen. This study used a maternal hypoxia-induced mouse model of IUGR to determine the combined effects of IUGR and allergy on airway responsiveness.

Research

Agreement between the DDD and vial-based measures of use supports the use of DDD for select antibiotics that may be targeted by antimicrobial stewardship programs

Research

The aim of this study is to identify and quantify the preferences of patients with cystic fibrosis regarding treatment outcomes

Research

Child maltreatment allegation is common in children following a maternal hospitalisation for assault

Research

The type of oral steroid seems to have no clinically significant impact on efficacy, both acutely and during the week after treatment

Research

This review examines the role of T cells in lung cancer, discussing the direction and clinical significance of current and future immunotherapeutic strategies

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Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system

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Substantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia

Research

The onset of psychosis was not associated with deterioration in cognitive ability

Research

Influenza is the most common vaccine-preventable disease in Australia, causing significant morbidity and mortality. We assessed the burden of influenza across all ages in terms of influenza-associated mortality and hospitalizations using national mortality, hospital-discharge and influenza surveillance data.