Search
Research
Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart diseaseGenomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.
Research
Skin-Microbiome Assembly in Preterm Infants during the First Three Weeks of Life and Impact of Topical Coconut Oil ApplicationThe structure and function of infant skin is not fully developed until 34 weeks of gestation, and this immaturity is associated with risk of late-onset sepsis (LOS). Topical coconut oil improves preterm-infant skin integrity and may reduce LOS. However, data on early-life skin-microbiome succession and potential effects of emollient skin care in preterm infants are scarce.
Research
Investing in school readiness: A comparison of different early childhood education pathways in rural IndonesiaThis paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways
Research
A population health approach in education to support children's early development: A Critical Interpretive SynthesisThe results from this review indicate that it would indeed be plausible to adapt the population health approach to sites and schools
Research
Patterns of multiple risk exposures for low receptive vocabulary growth 4-8 years in the Longitudinal Study of Australian ChildrenOur results demonstrate a range of multiple risk profiles in a population-representative sample of Australian children and highlight the mix of risk factors faced by children
Research
Birthweight and the risk of childhood-onset type 1 diabetesWe investigated whether children who are heavier at birth have an increased risk of type 1 diabetes
Research
Birth outcomes and academic achievement in childhood: A population record linkage studyThis study used population-based record linkage to examine the association between early life risk factors and academic achievement.
Research
Developmental Mismatch Across Brain Modalities in Young ChildrenBrain development during the preschool period is complex and extensive and underlies ongoing behavioral and cognitive maturation. Increasing understanding of typical brain maturation during this time is critical to early identification of atypical development and could inform treatments and interventions.
Research
Residential mobility amongst children and young people in Wales: A longitudinal study using linked administrative recordsChild poverty remains a major global concern and a child's experience of deprivation is heavily shaped by where they live and the stability of their local neighbourhood. This study examines frequencies and patterns of residential mobility in children and young people at a population level using novel geospatial techniques to assess how often their physical environment changes and to identify geographical variations in social mobility.
Research
Breastfeeding and early child development: A prospective cohort studyBreastfeeding has been associated with multiple developmental advantages for the infant; however, there have also been a number of studies that find...