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Research

Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system

Research

Spatial clustering of notified tuberculosis in Ethiopia: A nationwide study

Substantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia

Research

Gender-affirming hormones and surgery in transgender children and adolescents

This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children

Research

The public health control of scabies: priorities for research and action

Scabies causes considerable morbidity and leads to severe bacterial infection and immune-mediated disease

Research

Upper Airway Pathology Contributes to Respiratory Symptoms in Children Born Very Preterm

The upper airway may play a role in the respiratory symptoms experienced by some very preterm children and should be considered by clinicians

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The Brain Basis of Comorbidity in Neurodevelopmental Disorders

This review discusses early brain development and the etiological factors that may give rise to atypical developmental trajectories, along with neuroimaging insights

Research

Association between interpregnancy interval and adverse birth outcomes in women with a previous stillbirth: an international cohort study

Conception within 12 months of a stillbirth was common and was not associated with increased risk of adverse outcomes in the subsequent pregnancy

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CF derived scoring systems do not fully describe the range of structural changes seen on CT scans in PCD

Structural changes identified on CT scans in primary ciliary dyskinesia are not identical to those previously described in cystic fibrosis patients

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Protection against maternal infection-associated fetal growth restriction: Proof-of-concept with a microbial-derived immunomodulator

This study suggests that broad-spectrum protection-of-pregnancy against infection-associated inflammatory stress represents an achievable therapeutic goal

Research

Characterizing the risk of respiratory syncytial virus in infants with older siblings: a population-based birth cohort study

Our results lend support to a vaccination strategy which includes family members in order to provide maximum protection for newborn babies.