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News & Events

Researchers unlock BCG vaccine puzzle in findings that could save millions of newborns

The Kids Research Institute Australia researchers working with a global team have identified the mechanism behind one of science’s most enduring mysteries.

News & Events

WA first international hub for Human Vaccines Project

Thanks to a partnership with Perth Children’s Hospital Foundation, Perth’s The Kids Research Institute Australia will be at the forefront of a global push to decode the human immune system to transform how we prevent, diagnose and treat disease as the first international hub of the Human Vaccines Project.

News & Events

Global war on brain cancer

Dr Nick Gottardo and Dr Raelene Endersby from The Kids Research Institute Australia are the driving force behind an innovative, global action group on child brain cancer.

News & Events

On a quest for kids with cystic fibrosis

PRAGMA-CF, a new way of measuring early lung disease in young kids with cystic fibrosis is changing the way we detect and treat CF.

News & Events

Global research for rare disorder

The Kids Research Institute Australia researchers set out on a worldwide search to find out all they could about Rett syndrome, establishing databases and creating awareness.

News & Events

That goosebump moment

The Kids successfully pushed for the mandatory fortification of flour in Aus with the vitamin folic acid for the primary prevention of neural tube defects

Research

A controlled human infection model of Streptococcus pyogenes pharyngitis (CHIVAS-M75): an observational, dose-finding study

Streptococcus pyogenes is a leading cause of infection-related morbidity and mortality. A reinvigorated vaccine development effort calls for new clinically relevant human S pyogenes experimental infection models to support proof of concept evaluation of candidate vaccines. We describe the initial Controlled Human Infection for Vaccination Against S pyogenes (CHIVAS-M75) study, in which we aimed to identify a dose of emm75 S pyogenes that causes acute pharyngitis in at least 60% of volunteers when applied to the pharynx by swab.

Research

Stillbirth and neonatal death rates across time: The influence of pregnancy terminations and birth defects in a Western Australian population-based cohort study

Changes in clinical practice related to pregnancy terminations have played a substantial role in shaping stillbirth and neonatal death rates in WA