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Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemiaRearrangement of the mixed-lineage leukemia gene (MLL) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and re
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Fetal androgen exposure and pragmatic language ability of girls in middle childhoodPrenatal exposure to testosterone has been shown to affect fetal brain maturation as well as postnatal cognition and behavior in animal studies.
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AP-1 inhibitory peptides attenuate in vitro cortical neuronal cell death induced by kainic acid.This study has assessed the neuroprotective efficacy of five AP-1 inhibitory peptides in an in vitro excitotoxicity model.
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High tidal volume ventilation is not deleterious in infant rats exposed to severe hemorrhageBoth high tidal volume (V(T)) ventilation and hemorrhage induce acute lung injury in adult rodents. It is not known whether injurious ventilation augments lung
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Addison Disease – diagnosis and initial managementAdrenal insufficiency is a rare disease caused by either primary adrenal failure (Addison disease) or by impairment of the hypothalamic-pituitary-adrenal axis
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The Dyslexia Candidate Locus on 2p12 Is Associated with General Cognitive Ability and White Matter StructureTo further explore the effect of disorder-associated genes on cognitive functions, we investigated whether they play a role in broader cognitive traits.
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Young adults with intellectual disability transitioning from school to post-school: A literature review framed within the ICFThe purpose of this review was to describe literature relating to transition for young people with an intellectual disability and identify knowledge base gaps.
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The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways.
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Guidelines for pregnancy: What's an acceptable risk, and how is the evidence (finally) shaping up?This paper reviews the evidence from systematic reviews and meta-analyses examining the risk from low and moderate levels of prenatal alcohol exposure.
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Hypoallergenic der p 1/Der p 2 combination vaccines for immunotherapy of house dust mite allergyMore than 50% of allergic patients have house dust mite (HDM) allergy.