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Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart disease

Genomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.

“It just Sends the Message that you’re Nothing but your body” a Qualitative Exploration of Adolescent Girls’ Perceptions of Sexualized Images on Social Media

This qualitative study used in-depth interviews to explore adolescent girls’ perceptions of sexualized images they typically find when using social media. Twenty-four participants aged 14–17 years described sexualized images of females as normalized on social media. The interplay between gendered and social norms that endorsed and rewarded girls for posting sexualized images was seen to influence an expectation for girls to conform with their peers and post such images of themselves.

Built Environments And Child Health in WalEs and AuStralia (BEACHES): a study protocol

Childhood obesity and physical inactivity are two of the most significant modifiable risk factors for the prevention of non-communicable diseases. Yet, a third of children in Wales and Australia are overweight or obese, and only 20% of UK and Australian children are sufficiently active.

Incorporating Children's Voices

Informing urban planning and policy development to grow equitable access to healthy environments for young people and their families.

Play Active Program

Physical activity is critical during the early years of life for a child’s health and development.

Play Active Program – physical activity policy and training for Early Childhood Education and Care

Play Active is a national, low-cost, evidence-based program to boost energetic play in early childhood education and care. It offers free professional development for educators.

PLAYCE

With rising levels of physical and mental health issues, ensuring children establish good physical activity behaviours early in life is more important than ever.

PLAYCE Cohort Study: Moving well for optimal child health and development

The PLAYCE Cohort was established to investigate how movement behaviours change over early to late childhood, across key behaviour settings and relationships with health and development