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Preparing for Life: Plasma Proteome Changes and Immune System Development During the First Week of Human LifeNeonates have heightened susceptibility to infections. The biological mechanisms are incompletely understood but thought to be related to age-specific adaptations in immunity due to resource constraints during immune system development and growth. We present here an extended analysis of our proteomics study of peripheral blood-plasma from a study of healthy full-term newborns delivered vaginally, collected at the day of birth and on day of life (DOL) 1, 3, or 7, to cover the first week of life. The plasma proteome was characterized by LC-MS using our established 96-well plate format plasma proteomics platform.
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A platform in the use of medicines to treat chronic hepatitis C (PLATINUM C): protocol for a prospective treatment registry of real-world outcomes for hepatitis CSafe, highly curative, short course, direct acting antiviral (DAA) therapies are now available to treat chronic hepatitis C. DAA therapy is freely available to all adults chronically infected with the hepatitis C virus (HCV) in Australia. If left untreated, hepatitis C may lead to progressive hepatic fibrosis, cirrhosis and hepatocellular carcinoma.
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Complicated skin and soft tissue infections in remote indigenous communitiesThe burden and consequences of skin infections for remote living indigenous people are high
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Antibiotic appropriateness and guideline adherence in hospitalized children: results of a nationwide studyInappropriate antimicrobial prescribing in children was linked to specific risk factors, presenting opportunities for targeted interventions to improve prescribing
Research
Meningococcal B vaccine and meningococcal carriage in adolescents in AustraliaAmong Australian adolescents, the 4CMenB vaccine had no discernible effect on the carriage of disease-causing meningococci, including group B
News & Events
Decades-old work picked up by Google’s DeepMind leads to global scientific breakthroughA researcher's work from 20 years ago has helped to crack one of biology’s biggest mysteries.
News & Events
Multi-million-dollar investment in child health to support vital researchFour The Kids Research Institute Australia researchers have received prestigious fellowships and four significant cohort studies led or co-led by The Kids have received key grants under two new funding programs supported by the State Government’s Future Health Research and Innovation (FHRI) Fund.
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Leading disease modeller appointed inaugural Fiona Stanley Chair of Child Health ResearchThe Kids Research Institute Australia and The University of Western Australia are proud to announce the appointment of the inaugural Fiona Stanley Chair of Child Health Research, Professor Melissa Penny.
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Call for national newborn screening for little-known CMV virusWestern Australian researchers advocate for a national newborn screening program for congenital CMV to prevent hearing loss and related disabilities in infants.
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The Kids Research Institute Australia researcher recognised for saving children in PNGClinical Associate Professor Deborah Lehmann has been recognised for her dedication to reducing the burden of infectious diseases in Papua New Guinea (PNG) with an award supporting research in the Western Pacific named in her honour.